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Ulcerative Colitis Retrospective Study Of Risk Factors Associated With Phlegm Exploration

Posted on:2014-02-09Degree:MasterType:Thesis
Country:ChinaCandidate:Y XuFull Text:PDF
GTID:2264330425974684Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Purposes:Based on the review analysis in patients with ulcerative colitis clinical condition,traditional Chinese and western medicine for ulcerative colitis clinical characteristics and the physicaland chemical inspection is analyzed and summarized, to explore the relationship between ulcerativecolitis pathogenesis factors and the phlegm and blood stasis.Materials and methods:This study applies the liaoning university of traditional Chinesemedicine affiliated hospital medical record retrieval system, retrieval in July,2007-December2012,liaoning university of traditional Chinese medicine affiliated hospital of hospitalized cases that diagnosedwith ulcerative colitis, eventually were included in a total of81cases of ulcerative colitis cases. Toinclude cases (including age, gender), the basic situation of the clinical manifestations (complained ofsymptoms, clinical type), the physical and chemical indicators (platelet count, prothrombin time,fibrinogen), colonoscopy, suffering from lung disease, and treatment of traditional Chinese medicineclinical of data are collected and recorded to a database of Microsoft Excel spreadsheets, for sorting data.patients with clinical manifestations and clinical classification of statistical description. To accept Chinesemedicine treatment of ulcerative colitis patients according to whether the application of expellingdampness phlegm, promoting blood circulation to remove blood stasis drugs are grouped, as phlegmand dispelling the blood stasis group and control group, the root of different group of patients withplatelet count (PLT) and blood coagulation functions (including fibrinogen FIB, prothrombin time,PT)carries on the analysis of variance, and efficient for two groups of cases (complete response+ease) X2test. Apply statistical package SPSSl7.0for statistical processing. P <0.05, with statistical significance.Results:1. General situation:81patients were included in this study, male to female ratio of1:1.189, good hairages30to39years old. 2. The clinical classification:10cases of incipient stage (12.35%),4cases of chronic type (4.94%),67cases of chronic relapse type (82.71%), no cases of outbreak type.3. Clinical symptoms: the main symptoms of incipient style are abdominal pain, diarrhea, tenesmus,mucous purulent blood, heat, anus urine short red, red tongue, yellow moss greasy, pulse number. Themain symptoms of chronic continuous type and chronic relapse type are abdominal pain, tenesmus,mucous purulent blood, abdominal distension, less food, stay, languid, face yellow, pale tongue dark orhave teeth marks, the tongue body visible in petechiae, ecchymoses, veins thin or dry.4. Traditional Chinese medicine treatment group effective rate was69.39%; Phlegm and dispellingstasis group efficiency87.50%. The comparison was statistically significant (P <0.05).5. The physical and chemical inspection: in patients with ulcerative colitis, platelet count, fibrinogen,phlegm and dispelling of the blood stasis group was higher than the control group, the difference wasstatistically significant (P <0.05); Phlegm and dispelling stasis group of prothrombin time lower than thecontrol group, the difference was statistically significant (P <0.05).6. Lung disease and findings: in this study included81cases of, only a case found pneumonia, theclinical symptoms of chest tightness, NaCha, fatigue, red tongue moss white, pulse string.Conclusions:1. In this study, ulcerative colitis incidence between men and women have no distinction; The diseasecan occur at any age, but mostly in young adults.2. In this study with the highest proportion of chronic relapse type.It reflects recurrent,refractorylingering of pathogenic characteristics of phlegm and blood stasis.3. Chronic recurrent or chronic type has clinical symptoms of phlegm and blood stasis pathogenesis,disease just reflects the ulcerative colitis associated with phlegm and blood stasis.4. Add the formulas of phlegm and remove blood stasis drugs curative effect is better than that ofwithout the curative effect of phlegm and remove blood stasis drugs. Israel (medicine) measurementcertificate, phlegm and blood stasis is associated with the pathogenesis of ulcerative colitis.5. Application of expelling dampness phlegm, promoting blood circulation to remove blood stasis drugsof ulcerative colitis patients at the same time there are likely to be high coagulation state, one of the factors with the onset of ulcerative colitis "blood stasis" are similar.6. In the study included81cases, only one case of pneumonia appears after the illness, according to the"lung and large intestine list" of traditional Chinese medicine theory, the future may enlarge sample sizestudies whether the disease associated with the lungs.
Keywords/Search Tags:Ulcerative colitis, A retrospective analysis, Phlegm wet and Blood stasis, pathogenesis
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