| Objective:To investigate the effect of tian ma gou teng decoction on the cervical spondylotic arteriopathy(CSA),and to study the effective mechanism for the popularization and application of the drug to provide a scientific basis.Methods:from January 2009 to August 2009 in Beijing University of Chinese Medicine Dongzhimen Hospital affiliated or thopedic outpatient and inpatient treatment of cervical spon dylotic arteriopathy(CSA) in 61 cases, and were randomly divided into treatment group (tian ma gou teng decoction) and the control group (Sibelium) groups, in which the treatment group 32 cases, giving tian ma gou teng decoction treatment, A day, morning and evening services, control group 29 patients given Sibelium treatment.1 dose a day, Each oral 5mg, Tian ma gou teng decoction and the Sibelium Were purchased from Beijing University of Chinese Medicine Dongzhimen Hospital affiliated Pharmacy, A month later observed changes in symptoms and signs, and TCD.Results:The treatment group after treatment, the main symptoms (dizziness) the effective rate was 100%, while the control group was 79.3%, by Ridit analysis, P<0.01, The two groups had significant differences. Right shoulder and neck discomfort, headache, neck shoulder mus cle tenderness to improve the situation, the treatment group compared with the control group were significantly different, P<0.01。Treatment group, forgetful of insomnia, tinnitus and deafness, nausea and vomiting, blurred vision, and neck rotation test the efficacy, but also to im prove significantly compared with control group by statistical analysis, P<0.05, The remain ing symptoms and signs associated with the change Although there is no statistically significant difference in the two groups, However, the degree of improvement in treatment group than the control group. Explain the treatment and control groups improvement in clinical symptoms and signs are obvious effects, but the treatment group and the control group Statistical analysis, P <0.05, There was a significant difference, Tian Ma Gou Teng decoction can be more signify cantly improved CSA of clinical symptoms and signs, not found in the clinical observation of patients treated symptoms occur, and the recurrence rate is low, indicating Tian Ma Gou Teng decoction to improve the liver yang-type CSA in patients with symptoms and signs there is a genuine effect, and can prevent CSA, no side effects could be long-term use. Tian Ma Gou Te ng decoction on vertebral-basilar artery system peak systolic velocity (Vs), diastolic peak flow velocity (Vd), pulsatility index (Pi) than that before treatment improved, The treatment group in which left and right vertebral arteries and basilar artery after treatment of the Vs, Vd signify cant difference compared with before treatment (P<0.01), Left and right vertebral arteries and basilar artery after treatment than before treatment Pi significant difference (P<0.05); Control group, the left vertebral artery after treatment of the Vs, Vd significant difference compared with before treatment (P<0.01), The left vertebral artery after treatment than before treatment Pi significant difference (P<0.05), the right vertebral artery after treatment Vs, Vd, Pi compared with before treatment there was significant difference (P<0.05), Basilar artery after treatment Vd. Pi compared with before treatment there was significant difference (P<0.05), Between the two groups, treatment group, the left and right vertebral artery after treatment compared with the control group Vd significant difference (P<0.01), Treated group after trea-tment of basilar artery Vs, Vd compared with the control group were significantly different (P<0.05), Tian Ma Gou Teng decoction can improve the vertebro basilar artery blood flow, and have a certain role in reducing vascular resistance, which regulate vertebral artery are obviously superior to the control groupConclusion:we can see that Tian Ma Gou Teng decoction can be more signify-cantly imp roved the symptoms and signs of cervical spondylosis of cervical spondylotic arterio pathy (CSA), to improve the vertebral artery, regulating microcirculation, increase cerebral blood flow. |
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