| Objective:Based on the current situation of air pollution and the sleep quality of the middle-aged and old people in China,through epidemiological investigation to explore whether the exposure of PM2.5 will affect the sleep quality of the middle-aged and old people in China.To determine the sensitive population whose sleep quality is easily affected by PM2.5 exposure,so as to provide reference for improving the sleep quality of middle-aged and old people in China.Methods:Based on the project of"Research on acute health risk of air pollution in China-environmental health risk assessment in typical pollution areas",27 survey sites in the coverage area of"three areas and ten groups"of air pollution prevention and control in China were used to collect air pollution data of monitoring stations as exposure factors,and PSQI was used to collect sleep quality of survey objects as outcome variables;Collect the personal health,social and economic information of the respondents as confounding factors.Based on the above data,the relationship between atmospheric PM2.5 exposure and sleep quality was analyzed by using the generalized linear mixed effect model,and the relationship between atmospheric PM2.5 exposure and sleep quality in different subgroups was explored by using stratified analysis to determine the sensitive population.Results:?1?Basic information of the respondents:There were 3849 respondents in the first round,3956 in the second round and 3164 in the third round,a total of 10969respondents.In the baseline surveys,the average age was 63.7±13.6 years old,1899men?49.34%?and 1950 women?50.66%?.?2?PM2.5 concentration distribution:During the study period,the total PM2.5exposure concentration in each study area was 45.61±18.67?g/m3,and the exposure concentration range was 16.10118.69?g/m3.In January,November and December of 2018,the exposure concentration was the highest.?3?Sleep quality:The overall level of PSQI score was 3.97±3.19,with each component showing that,The scores of sleep time,self-rated sleep quality and sleep disorders were higher;The number of sleep disorders was 2769?25.24%?,and there were statistical differences in gender,age,marital status,annual family income,education,occupation,smoking,drinking,chronic disease and anxiety;the overall level of sleep duration was 7.46±1.27 hours,The sleep duration of the subjects in this study is on normal level.?4?Correlation analysis results:In the correlation analysis of this study,after adjusting the confounding factors,it shows that the lag effect of atmospheric PM2.5exposure on sleep disorders is limited to a certain extent.Only when PM2.5.5 exposure lags 30 days,the OR value of sleep disorders risk is 1.13?95%CI:1.041.23?for every 10?g/m3 of concentration increase.There was no statistical significance in the results of 60 day and 90 day exposure.However,for every 10?g/m3 increase of PM2.5exposure on 30 day,60 day and 90 day,the sleep duration decreased by 0.09 hours?95%CI:-0.11-0.06?,0.05 hours?95%CI:-0.08-0.03?,and 0.07 hours?95%CI:-0.09-0.04?;stratified analysis of female population?OR=1.15,95%CI:1.051.28?,young elderly population?OR=1.21,95%CI:1.051.38?,lean population?OR=1.15,95%CI:1.031.28?,chronic disease population?OR=1.29,95%CI:1.141.45?and non-smoking population(OR=1.17,95%CI:?1.061.28?.PM2.5 exposure was significantly associated with the risk of sleep disorders..Conclusion:The results of this study show that the increase of one month cumulative exposure concentration of atmospheric PM2.5 is related to the increase of the risk of sleep disorders,among which women,the young elderly,the lean,the people with chronic diseases,and the people without smoking are the high-risk groups.In addition,PM2.5 exposure to the people without sleep disorders will increase the incidence of sleep disorders,and reduce the incidence of sleep disorders Duration.The results of this study suggest that PM2.5 exposure should be avoided to improve sleep quality. |
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