Clinical Observation Of Warm Moxibustion Interpose In Leucopenia By Chemotherapy Of Colorectal Cancer

Objective:Observation of warming moxibustion intervene in the colorectal cancer patients with leukopenia which caused by the chemotherapy regimens:mFOLFOX6.Methods:1. From2013May to2013December in the Third Affiliated Hospital of Nanjing University of Chinese Medicine between hospitalized oncology patients, all cases were confirmed by electronic colonoscopy and biopsy, and after radical operation, postoperative adjuvant chemotherapy, TCM syndrome differentiation of spleen kidney yang deficiency.60cases were randomly divided into mild moxibustion group and blank control group, the mild moxibustion group30, control group30, two groups of patients showed no significant difference in gender, age, course and severity.2. Mild moxibustion groups:chemotherapy and mild moxibustion operation. Blank control group:simple chemotherapy. Records of two patients in the first analysis of blood cells4mFOLFOX6chemotherapy,(blood) WBC count, neutrophil (neutrophil, NEU) count value change, and observe the changes in patients with TCM syndrome. When the chemotherapy before the count of WBC<4x109/L, were treated with recombinant human granulocyte colony stimulating factor (Recombinant Human Granulocyte Colony-Stimulating Factor Injection, rhG-CSF) Shengbai support treatment, and record the dose.Results:The end of6the first mFOLFOX program after four treatments,1of mild moxibustion group intervention to reduce the total efficiency of WBC is higher than that of the blank control group, two groups of intervention to reducethe total efficiency of WBC showed no statistical significance (P>0.05),2mild moxibustion group using rhG-CSF total dose is lower than the blank control group, two groups of total dose is no significant significance (P>0.05).3mild moxibustion group of TCM syndrome compared with blank control group.4two groups in the third mFOLFOX6after chemotherapy (sixth data) WBC count began to appear obvious difference.Conclusions:1mild moxibustion stimulating Zusanli, Yongquan point, on the4mFOLFOX6CRC patients after adjuvant chemotherapy leukopenia with intervention, but there was no statistical difference.2patients received a high degree of mild moxibustion, no medication and drug injection produces physiological and psychological burden of patients, chemotherapy when the body to maintain or have a certain effect to improve, for clinical application. The clinical observation of3data show that there are differences, but not statistically significant, said the lack of experimental design, need to improve.4for mild moxibustion operation, operating parameters and influence mechanism of literature lacks, such as skin temperature control, moxibustion time and frequency of operation on the curative effect and so on, is worth further research and improvement.