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Clinical Research On Xiaoqinglong Granula In Treating Mild-to-moderate Bronchial Asthma

Posted on:2012-05-26Degree:MasterType:Thesis
Country:ChinaCandidate:H C HeFull Text:PDF
GTID:2154330335468015Subject:Chinese medicine
Abstract/Summary:PDF Full Text Request
ObjectiveIn order to evaluate the efficacy and safety of Xiaoqinglong Granula in treating mild-to-moderate Bronchial Asthma, through comparing the treatment group, treating with Xiaoqinglong Granula and Seretide, and the control group, treating with Seretide and placebo. To discuss the optimal indications of Xiaoqinglong Granula. In order to provide Clinical evidence Of integrated traditional Chinese and western medicine in treating Bronchial Asthma. In order to provide reference on the reform of the Chinese medicine's formulations.Methods30 patients with mild-to-(?)oderate bronchial asthma were randomly divided into Xiaoqinglong Granula group and the convent ional western medicine group.The disease condition, the syndrome integral, the TCM symptoms, the improvement of pulmonary function and the safety of medication were evaluated in both group after the theray for a week and for a month. In addition the quality of life were evaluated in both group after the theray for a month. In order to evaluate the safety of Xiaoqinglong Granula in treating Asthma, routine blood,stool examination,urine check,liver and kidney function testing,chest fluoroscopy and electrocardiogram would be done before treating and after treating for a month.Results There had no significant difference among the effective rates of the two groups (P> 0.05); The asthma symptoms and pulmonary function were improved in both group after treatment,but there had no significant difference among the accumulated score of asthma symptoms of the two groups (P> 0.05). There had significant difference among physical sign(coughing; expectoration) of the two groups after treatment (P< 0.05). There had significant difference among the accumulated score of the TCM symptoms and the quality of life of the two groups after treatment (P< 0.05), and the treatment group, is better than the control group. The side effect was not observed in both groups.ConclusionThis indicates that Xiaoqinglong Granula had a better curative effect on improving symptoms than the conventional western medicine group. Especially, the Xiaoqinglong Granula effect on the coughing,expectoration and the improvement of the TCM symptoms and the quality of life were better than compared group. And this also indicates the therapies in both groups are safe.
Keywords/Search Tags:bronchial asthma, mild-to-moderate, Xiaoqinglong Granula, asthma symptoms, the TCM symptoms, the quality of life
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