Clinical Observation And Mechanism Discussion On Jianpiwenshen Soup In Treating Deficiency Of Yang Of Both Spleen And Kidney Syndrome Of Irritable Bowel Syndrome (Diarrhea Type)

Objective: To observe the security and clinical efficacy of treating Yang of Both Spleen and Kidney Syndrome of Irritable bowel Syndrome (diarrhea type) with Jianpiwenshen soup. Method: Divided 60 patients of standards into 2 groups randomly, Each group has 30 patients.Jianpiwenshen soup is taken by each patients in treatment group, Gubenyichang oral tablets are taken by each patients in control group. Both groups were treated for thirty days,No other medicine is taken during this period. Both groups were given psychological counseling and dietary guidance during this period.To observe the clinical symptoms, signs and safety indicators such as blood, urine, heart, liver, renal functions.Two groups were maken a comparative analysis.Results: The treatment group clinical total effective rate was 90.00 percent, 83.33 percent for the control group, after statistical treatment, no significant difference (P> 0.05); two groups of patients with curative effect of TCM Syndrome comparison, statistical treatment, there is significant differences (P<0.05); the treatment group in improving the diarrhea after abdominal,chills,fart,pulse area by t test,there is significant difference(P<0.05);Two groups of patients with emotional symptoms before and after treatment ,the treatment group in the emotional status of the spirit of improving the situation is better than the control group; two groups after treatment gastrointestinal barium through the whole time and colonic transit time were prolonged, compared with before treatment there is significant (P <0.05), the treatment group in improving the balance of gastrointestinal motility is better than the control group. Conclusion: Jianpiwenshen soup can effectively alleviate a variety of symptoms of deficiency of yang of both spleen and kidney syndrome of irritable bowel syndrome(diarrhea type), without adverse reaction, its mechanism may be related to regulation of gastrointestinal motility, visceral hypersensitivity to reduce , bacteriostasis, regulate immune function and so on.