| Purpose:Objective To observe the clinical efficacy of Wang’s Jieyong Decoction in the treatment of anal carbuncle of heat toxin accumulation type,and to provide evidence and reference for the establishment of a more effective treatment scheme.Methods: according to the random number table,82 patients with anal carbuncle of heat toxin accumulation type were randomly divided into treatment group and control group.The treatment scheme of treatment group was retention enema of Wang’s Jieyong Decoction and intravenous drip of cefotaxime sodium for 5 days plus external application of Sanhuang Ointment,while the control group was intravenous drip of cefotaxime sodium for 5 days plus external application of Sanhuang Ointment.The curative effect,symptoms and signs of the two groups before treatment,7 days and 14 days after treatment were compared and recorded.Spss20.0 software was used for statistical analysis and comparison.According to the two treatment schemes,we made a scientific evaluation on the effect of Wang’s Jieyong Decoction in the treatment of early heat toxin accumulation anal carbuncle.Results:During the experiment,there were 4 cases in the experimental group and 4 cases in the control group,and 74 cases completed the study,including the treatment group(n = 37)and the control group(n = 37).Before treatment,the gender,age,perianal pain,systemic symptoms,tumor size,tumor texture of the two groups were compared,and the differences were not statistically significant.The baseline of the two groups was consistent and comparable.The results are as follows:(1)Comparison of the overall efficacy of the two groups: in the treatment group,28 cases were cured,5 cases were markedly effective,2 cases were effective and 2 cases were invalid;in the control group,20 cases were cured,3 cases were markedly effective,6 cases were effective and 8 cases were invalid.All P < 0.05,that is,there was significant difference in the overall efficacy between the two groups(P < 0.05),indicating that the overall efficacy of the treatment group was significantly better than that of the control group.(2)Comparison of clinical symptoms between the two groups: there were significant differences in the distribution of perianal pain and systemic symptoms between the two groups after 7 days and 14 days of treatment(P < 0.05).(3)The distribution of clinical signs of the two groups: there were significant differences in tumor size and texture between the two groups after 7 days and 14 days of treatment(P <0.05),and the curative effect of the treatment group was more significant.(4)Recurrence and adverse reactions: there was a significant difference in the recurrence data of the two groups after one month(P < 0.05),and the curative effect of the treatment group was more significant.No serious adverse reactions occurred during the study.Conclusion: Wang’s Jieyong Decoction in the treatment of early perianal subcutaneous abscess of heat toxin accumulation type,compared with the conventional treatment group,the results showed that the treatment group can significantly relieve perianal pain,systemic symptoms,improve the size and texture of the mass,especially in reducing local pain and improving the size of the mass,the research results of the treatment group were significantly better than the control group.It is an effective and relatively safe treatment method. |