Clinical Study On The Treatment Of Functional Constipation Induced By Qi Deficiency By Self-designed Fuyuan Decoction Under The Guidance Of The Theory Of Circular Movement Of Qi Mechanism Of Traditional Chinese Medicine

Objective:To evaluate the clinical efficacy of self-designed fuyuan decoction under the guidance of the theory of circular movement of qi mechanism of traditional Chinese medicineand compound polyethylene glycol electrolyte powder(Ⅳ)(trade name:shutaiqing)in the treatment of qi deficiency functional constipation.In order to provide diagnosis and treatment ideas for clinical prevention and treatment of functional constipation of qi deficiency type.Methods:From December 2019 to December 2020,60 patients with Qi deficiency functional constipation in anorectal Department of Affiliated Hospital of Shandong University of traditional Chinese medicine were randomly divided into treatment group and control group,30 cases in each group.The treatment group was given self-made fuyuan decoction orally,twice a day,200ml before meals in the morning and evening.The control group was given compound polyethylene glycol electrolyte powder(Ⅳ)(trade name:shutaiqing).The clinical symptom scores,curative effect results and recurrence rate were recorded before treatment,1 week,2 weeks,3 weeks and 3 months after treatment.During the treatment,other drugs were stopped.Clinical observation and evaluation of the two groups of drugs in the diagnosis and treatment of qi deficiency type of functional constipation.The defecation characteristics,defecation time,defecation frequency,defecation difficulty,incomplete defecation feeling,abdominal pain,abdominal fullness,mental fatigue,lack of Qi and lazy speech,and loss of appetite of the two groups were scored.Through statistical methods to sort out the data,analysis and draw conclusions.Results:1.There was no significant difference in gender composition and age distribution between the two groups(P>0.05).2.Before treatment,there was no significant difference between the two groups in stool characteristics,defecation time,defecation frequency,defecation difficulty,incomplete feeling of defecation,abdominal pain,abdominal fullness,mental fatigue,less gas and lazy speech,and symptom scores of anorexia(P>0.05).3.After one week of treatment,there were statistical differences in defecation time and abdominal fullness symptom score between the two groups(P<0.05).There was statistical difference in the total score of constipation symptoms between the two groups after 1 week of treatment(P<0.05),suggesting that the treatment group was better than the control group in improving constipation symptoms in general after 1 week of treatment.4.After 2 weeks of treatment,there were statistical differences in defecation time,defecation difficulty,abdominal pain,abdominal fullness,and anorexia symptom scores between the two groups(P<0.05).There was statistical difference in the total score of constipation symptoms between the two groups after 2 weeks of treatment(P<0.05),suggesting that the treatment group was better than the control group in improving constipation symptoms after 2 weeks of treatment.5.After 3 weeks of treatment,the symptom scores of constipation in the two groups were statistically different in defecation time,defecation difficulty,abdominal pain,abdominal fullness,mental fatigue,less Qi and lazy speech,and loss of appetite(P<0.05).There was statistical difference in the total score of constipation symptoms between the two groups after 3 weeks of treatment(P<0.05),suggesting that the treatment group was better than the control group in improving constipation symptoms after 3 weeks of treatment.6.Three months after the end of treatment,the symptom scores of constipation in the two groups were statistically different in the symptom scores of defecation type,defecation time,defecation difficulty,incomplete defecation feeling,abdominal pain,abdominal fullness,mental fatigue,less Qi and lazy speech,and anorexia(P<0.05).There was statistical difference in the total score of constipation symptoms between the two groups 3 months after the end of treatment(P<0.05),suggesting that the treatment group was better than the control group in improving constipation symptoms in general 3 months after the end of treatment.7.There was no significant difference in the overall clinical efficacy between the two groups after 3 weeks of treatment(P>0.05),but the total effective rate of the treatment group was better than that of the control group after 3 weeks of treatment.There was no statistical difference in the recurrence rate of the two groups 3 months after the end of treatment(P>0.05),but the recurrence rate of the treatment group was lower than that of the control group,indicating that the long-term effect of the treatment group was better than that of the control group.Conclusion:Both groups can improve the clinical symptoms of patients with Qi deficiency type functional constipation.The clinical effect of self-made fuyuan decoction group is more significant and the recurrence rate is low.There were no obvious abnormalities in general vital signs,blood routine,urine routine,stool routine,blood biochemistry and ECG before and after treatment in the two groups.No serious adverse reactions and complications were found in the two groups during the treatment,which is worthy of clinical promotion.