| Objective:This subject through Through to observe intestinal antidiarrheal party treat type change in the treatment of diarrhea type irritable bowel syndrome before and after the change of clinical symptoms,objective and real evaluation to change the type of IBS-D the efficacy and safety,for the treatment of Chinese medicine after dinner uncomfortable syndrome provide certain clinical basis,makes the treatment of the disease has become more abundant.Methods:The subjects of the study were 80 patients who attended the outpatient clinic of spleen and stomach clinic.And the hospital is Affiliated Hospital of Shanxi University of Traditional Chinese Medicine.The time of my shudy lasts for one year which begins in December 2019 and ends in January 2021.The patients of my study are thoes people who met the criteria for entry of diarrhea-type irritable bowel s-yndrome(liver stagnation and spleen deficiency syndrome).The patients of this study are divided into two groups and one group contains 40 cases named treatment group,the other group contains40 cases named control group randomly.Patients in the treatment group were given oral Anchang zhixie Recipe(1 dose a day,divided into the morning and evening on an empty stomach),and patients in the control g-roup were given Tongxiening Granules(5g/time,Tid,orally before meals).The trea-tment cycle was 4 weeks.Before and after treatment,the patients’ scores of TCM syndromes and major symptoms of Western medicine were recorded,and the data were sorted and compared after treatment.In this experiment,we select SPSS 22.0 to help this study,as the analytical and processed statistical software.Result:A total of 5 cases were lost from the study,and 37 cases in the experimental group and 38 cases in the control group were finally included in the statistical analysis.The general information(gender,age,course of disease,total score of pre-treatment symptoms)of the two groups were balanced and comparable at baseline.1.Comparison of the overall efficacy of TCM syndrome: The statistics of the efficacy scores of TCM syndromes was evaluated and analyzed.The total symptomatic effect rate of this study are divided into: 94.6% and 86.9%.And the higher of these belongs to the treatment group and another belongs to the control group.In contrast,the treatment group had obvious advantages.2.Comparison of TCM syndrome scores: intra-group comparison of the total TCM syndrome scores of the two groups showed P<0.05,indicating that both groups were effective in alleviating TCM syndrome manifestations of IBS patients with liver stagnation and spleen deficiency diarrhea.Comparison between groups showed that abdominal pain was diarrhea,pain reduction after diarrhea,impatience and irritability,abdominal distention and pain,and tolerance,P<0.05,indicating that the efficacy of Anchang Zhixie prescription group was better than that of Tongxiening granules group.In terms of fatigue and fatigue,P BBB 0.05 indicated that the two groups had the same curative effect.3.Comparison of scores of major symptoms in western medicine: intra-group and inter-group comparison of data in the two groups showed P<0.05,indicating that in terms of symptoms of western medicine,both treatment schemes could relieve abdominal pain and diarrhea symptoms of the disease,but the experimental group had better efficacy.4.Safety evaluation: In the two groups both of before or after treatment all have no adverse reactions.Conclusion : It is safe and effective that Anchang zhixie Decoction treates the diarrhea-type irritable bowel syndrome belonging to liver depression and spleen deficiency.It can effectively regulate gastrointestinal peristalsis,relieve mood,significantly improve the cure rate,and enrich the treatment methods.It is worthy of clinical promotion. |