Clinical Study On Nausea And Vomiting Caused By Postoperative Chemotherapy In Breast Cancer With Space-time Acupuncture Program Of Ling Turtle Eight Methods

Objective:In this study,postoperative breast cancer Chemotherapy patients as study object,through Space-time Acupuncture program of Ling Turtle Eight Methods and the difference between regular antiemetic use is compared,after chemotherapy with nausea and vomiting(chemotherapy-induced nausea and vomiting(CINV)).Metheds:According to the inclusion criteria,72 patients requiring chemotherapy after breast cancer surgery were selected.and 36 cases were randomly divided into treatment group.in the control group,36 cases patients were treated with regular antiemetic.the two groups use the same chemotherapy regimen,a total of 20 times of acupuncture.Patients in the control group received regular antiemetic 30 minutes before each chemotherapy for 8 times.Before chemotherapy,the grade of nausea and vomiting,Karnofsky score and EORTC QLQ-C30 quality of life questionnaire evaluation were analyzed.After each chemotherapy,the nausea and vomiting of the two groups were recorded.QLQ-C30 quality of life questionnaire was evaluated three weeks after the end of all 8 rounds of chemotherapy.All data collected were collated and statistically analyzed after chemotherapy.Results:1 A total of 72 patients were included in this study.During the experiment,5cases fell off in the treatment group and 6 cases in the control group,and 61 cases were actually included in the statistics.2 There was no statistically significant difference between the two groups in terms of age,weight,body surface area,heart rate and karnofsky score before chemotherapy(P>0.05).3 The nausea improvement rate of the treatment group was significantly higher than that of the control group after the 2nd,5th,6th,7th,8th chemotherapy(P<0.05),and the difference was statistically significant.The nausea improvement rate of the treatment group was lower than that of the control group after the 1st,3rd and 4th chemotherapy(P>0.05),and the difference was not statistically significant.After 8times of chemotherapy,the regular antiemetic effect of the treatment group was better than that of the control group(P<0.05),show statistical significance;4 In terms of Karnofsky score,there was a statistically significant difference in the score after 2-8 rounds of chemotherapy in the treatment group(P<0.05).In EORTC QLQ-C30(Version3),there was no statistically significant difference between the two groups in the core scale for quality of life measurement of cancer patients in the field of cognitive function treatment group and the field of diarrhea group(P >0.05),while there was statistically significant difference between the other groups(P<0.05).Conclusion:1 The effect of Space-time Acupuncture program of Ling Turtle Eight Methods on postoperative chemotherapy of breast cancer induced by spleen-deficiency and liver-depression type nausea and vomiting is better than of regular antiemetic;2 Space-time Acupuncture program of Ling Turtle Eight Methods can improve the Karnofsky score and the quality of life of breast cancer patients;3 Space-time Acupuncture program of Ling Turtle Eight Methods treatment of postoperative chemotherapy for breast cancer caused by spleen-deficiency and liver-depression type nausea and vomiting is significantly better than the regular antiemetic its effect is lasting,and can improve the patients in the chemotherapy process of other symptoms of discomfort,and with the patients throughout the chemotherapy cycle,clinical simple and easy to operate,can be applied in the clinical.