Analysis Of Related Factors Of Intracranial Infection After Craniotomy

Objective:Infection after neurosurgery is one of the most common complications.In order to reduce the incidence of infection after craniotomy,the clinical data of patients undergoing craniotomy in neurosurgery in our hospital were collected,and statistical methods were used for retrospective analysis to identify the risk factors for postoperative intracranial infection.Clinical treatment provides a reference.Methods:Retrospective analysis of 753 cases of postoperative craniotomy in the Department of Neurosurgery,the First Affiliated Hospital of Kunming Medical University from January 2017 to February 2018.140 cases of postoperative infection,including 41 cases of intracranial infection,selected this The clinical data of 100 uninfected patients after craniotomy were retrospectively analyzed,and the patient's relevant information was recorded in detail,including age,gender,emergency surgery,high blood pressure,diabetes,and continuous operation.Time,site of surgery(infratentorial/supratentorial),placement of drainage tube,location of drainage tube,Drainage time of the drainage tube,use of hormones during surgery,cerebrospinal fluid leakage,intraoperative blood transfusion,postoperative cerebrospinal fluid culture results,presence or absence Artificial implants,whether there is drainage of the waist pool.Firstly,the risk factors that may lead to intracranial infection after craniotomy were treated by single factor statistical method,and the statistically significant(P<0.05)analysis factors were screened.Factors with statistical differences were then processed by multivariate logistic regression analysisResults:In the 753 cases investigated,140 cases of postoperative infection occurred,including 41 cases of intracranial infection.The incidence of postoperative craniotomy was 18.59%,of which the proportion of pulmonary infection was the highest,and the incidence of intracranial infection was 5.44%.SPSS 24.0 did a single factor analysis found:gender,emergency surgery,combined with hypertension,diabetes,ventricular drainage,drainage time,hormone use,intraoperative blood transfusion,intracranial artificial implant,lumbar drainage and craniotomy There was no statistically significant difference in internal infection(P>0.05).There was a statistically significant difference in age(?50 years),surgery of infratentorial,Drainage tube drainage time(?3 days),cerebrospinal fluid leakage and intracranial infection after craniotomy.Multiple logistic regression analysis:the highest Wald X 2 value at the surgery of infratentorial was 8.573.The effect of subsurgical surgery on intracranial infection was the largest,followed by postoperative cerebrospinal fluid leakage(Wald X 2=8.498),age(Wald X2=6.465),drainage tube drainage.Time(Wald X2=5.938).The pathogen analysis showed that the infection of Gram-positive bacteria was the most common,with a ratio of 41.67%.Among Gram-positive bacteria,Staphylococcus aureus and Staphylococcus epidermidis had the highest proportion.Among Gram-negative bacteria,Acinetobacter baumannii has the highest proportion.Conclusion:In this study,age(?50 years),surgery of infratentorial,Drainage tube drainage time(?3 days),and cerebrospinal fluid leakage were independent risk factors for intracranial infection after craniotomy.Among them,surgery of infratentorial is the most important risk of intracranial infection Factors;In the pathogen study,infection with Staphylococcus aureus and Staphylococcus epidermidis in Gram-positive bacteria is the most common.