Analysis Of The High Risk Factors Of Intracranial Infection Of Posterior Fossa Tumor After Craniotomy In Neurosurgery

Objective: To investigate the high risk factors of intracranial infection in neurosurgery,and to provide reference for clinical prevention and control.Methods: From January 2014 to December 2019,281 patients who underwent selective posterior cranial fossa tumor craniotomy in neurosurgery of our hospital and met the exclusion criteria were collected as the total data,among which the data of 28 patients with intracranial infection occurred in the medical record group.84 patients were selected as control group according to 1:3 matching.Spss24.0 was used for single factor analysis and multivariate logistic regression equation analysis.Results: There were 28 cases of Post Craniotomy Intracranial Infection(PCII)in our hospital,and the infection rate was 9.96%.The patients were 38 minors,and the PCII occurred in 8 cases(21.0%).There were 243 adults,20 infected,and the infection rate was 8.2%.Logistic regression analysis showed that the operation time,ventricular drainage,cerebrospinal fluid leakage,wound healing,infection of other parts and opening of the fourth ventricle were statistically significant,among which cerebrospinal fluid leakage was the most influential factor.Conclusion:(1)the infection rate of PCII is 9.96%.(2)The incidence of PCII infection was higher in children.(3)The high risk factors of postoperative intracranial infection in Department of neurosurgery were operation time,ventricular drainage,cerebrospinal fluid leakage,poor wound healing and infection in other organ.Cerebrospinal fluid leakage is the NO.1 factor.