Study On The Risk Factors Of Intracranial Infection After The Neurosurgery Craniotomy

Objectives Many neurosurgeons have carried out the analysis of the factors that lead to intracranial infection after eraniotomy combined their hospital cases, However, due to the different hospital surgical environment and inpatient environment, the conclusions are different. Coupled with the implementation of new antibiotic regulations in recent years, statistical analysis of the patients" data of intracranial infection after eraniotomy in our hospital is necessary to discover the risk factors related to the infection, to reduce infection after eraniotomy,Methods Retrospectively analyze the459cases of patients after eraniotomy, who are of the same ward of Neurosurgery, Qilu Hospital, Shandong University, during December2011to November2012, and have detailed records to be investigated. In which22cases are postoperative intracranial infection, the infection rate was4.8%. Record the massage include gender, age, anesthesia, surgical site (supratentorial, infratentorial), operative time, operative time, postoperative drainage pipe, postoperative corticosteroids of all cases. Then use SPSS18univariate analyze the pre-quantitative risk factors,and screened the factors related to intracranial infection which have a statistically significant difference (P<0.05). Import these factors of statistically different into two logistic regression equation to do multivariate analysis, determine independent risk factor related to the intracranial infection after craniotomy.We can estimate the relationship between the independent risk factors and intracranial infection according to the calculated values of Exp (B).Results In the459Collected cases,22cases are infection, the infection rate was4.8%. Univariate analysis found:emergency surgery, operation time, infratentorial (posterior fossa) surgery, postoperative drainage tube, postoperative use of hormones, prophylactic antibiotics associated with intracranial infection,are factors of statistically significant difference (P<0.05).Import these factors of statistically different into two logistic regression equations for multivariate analysis,the results emergency surgery [Exp (B)=7.273], of this example, is the highest risk factors. Infratentorial (posterior fossa) surgery [Exp (B)=4.744], postoperative drainage tube [Exp (B)=4.002] and postoperative use of hormones [Exp (B)=2.910], They are also easily lead to intracranial infection. Preventive use of antibiotics [Exp (B)=0.232], is the protective factors prevent intracranial infection after craniotomy.Conclusion1, The factor leading to craniotomy postoperative infection can be single,or multiple. In this case, emergency surgery, infratentorial (posterior cranial fossa) surgery, postoperative drainage tube placement, postoperative use of hormones is the independent risk factors of intracranial infection, and preventive use of antibiotics is the protection factors.2, In this case,emergency surgery [Exp (B)=7.273], of this example, is the highest risk factors. Infratentorial (posterior fossa) surgery [Exp (B)=4.744], postoperative drainage tube [Exp (B)=4.002] and postoperative use of hormones [Exp (B)=2.910] are also easily lead to intracranial infection. Preventive use of antibiotics [Exp (B)=0.232]. is the protective factors prevent intracranial infection after craniotomy.