Clinical Study Of Shungan Lidan Decoction In Preventing Abdominal Pain And Abdominal Distension After Laparoscopic Cholecystectomy

Objective: To observe the effect of Shungan Lidan decoction on preventing Long-term abdominal pain and abdominal distension after laparoscopic cholecystectomy.Through this clinical study to prove the clinical effect of Shungan Lidan decoction,and to provide clinical basis for further application of Shungan Lidan decoction,in order to reduce the pain of patients treated with laparoscopic cholecystectomy.Methods:One hundred and twenty patients with benign gallbladder diseases undergoing laparoscopic cholecystectomy from August 2016 to August 2017 were selected from the General surgery Department of the affiliated Hospital of Chengdu University of traditional Chinese Medicine.They were randomly divided into control group and observation group with sixty cases in each group.The control group was only treated with routine western medicine after operation,that is,anti-infection,fluid infusion,maintenance of water and electrolyte balance and nutritional support for symptoms,etc.They began to eat after the anal exhaust.In addition to the routine treatment mentioned above,the observation group was treated with Shungan Lidan decoction on the second day after operation,three times per day,each 50 mL,30 days of continuous use.During the whole treatment,the tolerance of patients taking Shunganlitan decoction was observed,that is,the probability and degree of nausea and vomiting occurred in the patients from the second day to the 31 st day after operation.The index changes of liver function,renal function and CCK,MTL were monitored before and after operation?before and after taking Shungan Lidan decoction.And the occurrence of abdominal pain and distension?the number of biliary SOD(sphincter of oddi dysfunction,SOD)cases in the two groups were observed within one month to one and a half years after operation.At the same time,to observe the occurrence of adverse reaction.The statistical data were analyzed by SPSS22.0 statistical software.Results:1.The total probability of nausea and vomiting was28.3% in the control group and10.7% in the observation group during the treatment period,the difference was statistically significant,and the observation group was lower than that in the control group.2.During the treatment,the results of ALT,AST,BUN,Cr of the two groups fluctuated slightly,but within the normal range.3.Results of CCK,MTL in the two groups:the difference was statistically significant on the 3rd day after operation and 2 days before the operation,and the results of CCK,MTL was higher on the 3rd day after operation;the difference was statistically significant on the 31 st day and the 3rd day after the operation,and the results of CCK,MTL was lower on the 31 st day after the operation;in the control group,the difference was statistically significant on the 31 st day after operation and 2 days before the operation,and the results of CCK,MTL was higher on the 31 st day after the operation;there was no significant difference between the 31 st day after operation and 2days before the operation in the observation group.Two days before operation and 3 days after operation,there was no significant difference in the results of CCK,MTL between the two groups;On the 31 st day after operation,the difference was statistically significant,and the observation group was lower than the control group.4.Within one month to one and a half years after operation,the incidence of abdominal pain was 28.3% in the control group and 11.3% in the observation group;the incidence of abdominal distension was 26.4% in the control group and 11.3% in the observation group;the differences were statistically significant.5.Within one month to one and a half years after operation,the incidence of biliary SOD in the control group was 1.9%,and that in the observation group was 0.0%.The difference was not statistically significant.6.In this study,no significant adverse reaction events were observed.Conclusion:1.Shungan Lidan decoction had no obvious effect on liver function and renal function,and alleviated the incidence and symptom of nausea and vomiting after LC.It had good tolerance and no obvious adverse reaction.It has high safety to popularize and apply.2.Shungan Lidan decoction can reduce the incidence of early postoperative nausea and vomiting and Long-term abdominal pain and abdominal distension.