Clinical Randomized Controlled Study On The Improvement Of Abdominal Pain And Abdominal Distension In Acute Pancreatitis By Distal Point Selection

Objective:By comparing acupuncture at distal acupoints and non-meridional non-acupoints in patients with acute pancreatitis,the curative effect of acupuncture on relieving abdominal pain in patients with acute pancreatitis was verified,and the time effect of acupuncture at distal acupoints and abdominal pain in patients with acute pancreatitis was further explored,so as to provide evidence-based evidence for clinical selection and optimization of acupuncture timing.Methods:120 cases according to 1:1 participants were randomly assigned into two groups(60 cases in each group),the experimental group choose for distal acupuncture point combined with conventional treatment group,control group to without going through the acupuncture point combined with conventional treatment group,every morning to acupuncture,retaining needle for 30 minutes,every 15 minutes for a row needle,once a day,to get gas for degrees,acupuncture treatment for 3 consecutive days.VAS scores of abdominal pain and abdominal distension at 0 h,2 h,4 h,6 h,8 h and 22-24 h after acupuncture were the main observation indicators.On admission,72 hours of the CAR after admission(serum C reactive protein/albumin ratio),IL-6(Interleukin 6),PCT(Pancreatitis Activity Scoring System),the WBC(White blood cell Count),NEUT(neutrophil percentage),SOFA(Sequential Organ Failure score),SIRS(Systemic Inflammatory Response Syndrome),PASS(Pancreatitis Activity grading,);For 3 consecutive days,24-hour analgesic dosage,24-hour total fecal volume,and the time for the first voluntary anal defecation;The secondary observation indexes were mean length of hospital stay and organ failure.Results:1.The results of comparison of baseline data between the two groups were not statistically significant(P>0.05),and were comparable between the two groups.2.Changes of abdominal pain: on the first day,the distal acupuncture point was compared with each time point in the non-meridian-non-acupoint group at 0h,2h,4h and 6h,with statistical significance(P<0.05).On the second day,the comparison between the distal acupuncture points and each time point within 0h and 2h after acupuncture in the non-acupoint group showed statistical significance(P<0.05).Distal acupuncture acupoints and the third day after acupuncture without going through the acupuncture point group 0h,2h,4 h,6 h,8h and 22-24 h in each time point,are statistically significant(P<0.05).3.Changes of abdominal distension: on the first day,the distal acupuncture points were compared with each time point within 0h,2h,4h and 6h of the non-meridional nonacupoint group(P < 0.05).On the second day,the comparison between the distal acupuncture points and each time point within 0h and 2h after acupuncture in the nonacupoint group was statistically significant(P<0.05).Distal acupuncture acupoints and the third day after acupuncture without going through the acupuncture point group 0h,2h,4h,6h,8h and 22-24 h in each time point,are statistically significant(P<0.05).4.On the first day after acupuncture,the total amount of stool in the distal acupoint group was compared with that in the non-acupoint group,and the difference was statistically significant(P < 0.05).After the third acupuncture,the number of the first independent defecation was compared between the two groups 0-4h after acupuncture and 4-8h after acupuncture,and the difference was statistically significant(P<0.05).5.The difference value of IL-6 between distal acupuncture points and nonmeridians and non-acupuncture points before and after acupuncture was statistically significant(P<0.05).6.There was no statistically significant difference in the analgesic dosage,SOFA score,SIRS score and PASS score between the distal acupuncture points and acupuncture non-meridians and non-acupoints(P<0.05).Conclusions:Acupuncture of distal acupoints had an immediate effect on relieving abdominal pain and abdominal distension in AP patients,and the duration was at least 2h.Acupuncture at the distal acupoint can increase the total amount of defecation in patients for 24 hours,accelerate the reduction of il-6 level in AP patients,and inhibit the inflammatory response of AP.