Clinical Study On The Effect Of Guipi Decoction On Perioperative Recessive Blood Loss In Unilateral Total Hip Arthroplasty

Objective To compare the perioperative recessive blood loss and Hb and HCT values in patients with unilateral total hip arthroplasty by randomized controlled trials,and to evaluate the effect of Guipi Decoction on total hip arthroplasty patients.The influence of perioperative recessive blood loss provides a new way of thinking and methods for the treatment of hidden blood loss in perioperative period.Methods Patients who underwent primary total hip arthroplasty at the First Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine from February 2018 to January 2019 were enrolled.All patients enrolled in the study were divided into treatment group(Gengpi Decoction group,30 cases)and control group(blank control group,30 cases)according to the randomized distribution plan.All patients registered height,weight,preoperative Hb and HCT values before surgery.The treatment group received oral spleen decoction from 3 days before the total hip arthroplasty to 7 days after the operation.The control group only underwent total hip arthroplasty and did not take any Chinese medicine.The intraoperative and postoperative drainage volumes and the blood Hb and HCT values of the first,third and seventh days were recorded separately.The recessive blood loss was calculated by the Gross equation.The magnitude of the recessive blood loss was compared between the two groups.The effect of spleen soup on the amount of recessive blood loss.Results 1.There were no significant differences in age,height,weight,BMI,underlying disease,preoperative hemoglobin(Hb),and hematocrit(HCT)between the two groups(P>0.05).The clinical group was comparable.There was no significant difference in hemoglobin value(Hb)between the first day and the third day(P>0.05).The difference was not statistically significant.The hemoglobin value(Hb)was compared on the 7th day after surgery(P<0.05).The difference was statistically significant.On the 7th day after operation,the Hb value of the treatment group was significantly higher than that of the control group.3.The hematocrit value(HCT)on the 1st day after surgery(P>0.05),the difference was not statistically significant;On the 3rd and 7th day,the HCT values were compared(P<0.05).The difference was statistically significant.The hematocrit value(HCT)of the treatment group was significantly higher than that of the control group on the 3rd and 7th day after surgery.There was no significant difference in the amount of recessive blood loss between the 1st day and the control group(P>0.05).The difference was not statistically significant.The amount of recessive blood loss from the first day to the third day after surgery(P<0.05).),the difference was statistically significant,and the treatment group had less recessive blood loss than the control group;There was no significant difference in the perioperative significant blood loss between the treatment group and the control group(P>0.05).The difference was not statistically significant.The total perioperative blood loss and recessive blood loss were compared(P<0.05).The significance of the study,the total blood loss and recessive blood loss in the perioperative period of the treatment group decreased compared with the control group.Conclusion(1)Guipi Decoction can reduce the amount of recessive blood loss after total hip arthroplasty and improve the perioperative recessive blood loss in patients with joint replacement;(2)Guipi Decoction can promote the recovery of perioperative hemoglobin and hematocrit in patients undergoing total hip arthroplasty,and provide new ideas for the treatment of recessive blood loss in patients with joint replacement.It is worthy of clinical application and promotion.