The Clinical Observation Of Tangzhi Co-regulation Recipe Intreatment Of Type 2 Diabetes Mellitus With Dyslipidemia Humid-heat And Blood Stasis Syndrome

Objective: Under the guidance of Professor Piao Chun-li,through aiming at trea ting T2 DM with dyslipidemia humid-heat and blood stasis syndrome.which is based on kusuan tongtiao theory by clearing heat and promoting dampness and removing blood stasis and collaterals,Compared with the conventional western medicine,By o bserving the improvement of clinical symptoms,lowering the level of blood glucose,blood lipids?HbAlc and insulin resistance,and reducing the clinical effect of weight loss,this paper provides a theoretical basis and treatment method for the prevention and treatment of type 2 diabetes complicated with dyslipidemia by Chinese medicine.It is of importan meaning.Methods: On the foundation of lifestyle intervention,the patients were distribut ed two groups by random and contrast,treatment and control group,36 cases each.The treatment group was treated with TangZhi Co-regulation recipe,and the control group was given of metformin hydrochloride tablets orally for 4 weeks for a course of 3 courses.All the patients were in accordance with the clinical diagnostic criteria of Chinese and western medicine,and were screened according to the inclusion and exclusion criteria.Results:1.The total effective rate of the treatment group was 86.67%,and that of the control group was 73.33%,comparison between the two groups the treatment group was superior to the control group(P < 0.05).In terms of improving clinical symptoms of TCM,the treatment group(except fatigue and fatigue(P > 0.05))was superior to the control group(P < 0.01 or P < 0.05).In terms of improving symptom scores,both groups had significant curative effect(P < 0.01 or P < 0.05),and intergroup comparison the treatment group was significantly better than the control group(P< 0.01).2.In terms of regulating blood glucose and insulin resistance,FPG,2HPG,Hb Alc and c-peptide(fasting/postprandial)levels were significantly improved in both gr oups(P < 0.01),and there was no significant difference between the two groups(P> 0.05).3.In the improvement of lipid level,both groups had a certain effect(P < 0.01 or P < 0.05).Among the groups,the treatment group was significantly better than the control group in improving TC and LDL-C(P < 0.01).In terms of TG reducti on,the treatment group was superior to the control group(P < 0.05).There was no significant difference between the two groups at elevated HDL-C levels(P > 0.05).4.BMI and waist-to-hip ratio were significantly reduced in both groups(P < 0.01 or P < 0.05).The treatment group was superior to the control group(P < 0.05).No adverse reactions occurred during the experiment.Conclusion: The treatment of T2 DM with dyslipidemia by TangZhi Co-regulation recipe is effective.It can reduce FPG?2HPG and HbAlc level,it is effective in regulating lipid metabolism and improving the clinical symptoms of patients.It is safety and no toxic side effects,at the same time,it can improve the degree of insulin resistance,reduce body weight,and expand the new vision of TCM treatment of type 2 diabetes with dyslipidemia.