Effects Of Compound Sanqi Particles In TheTreatment Of Atherosclerosis And Its Effect On CAVI?IMT?ABI

Objective:Particles for observation compound panax notoginseng AS before and after treatment in patients with clinical symptoms and CAVI,the change of IMT and ABI and related inspection,AS the basis of evaluating the effect of kidney qi and treatment of the AS,at the same time explore the related mechanism.Method:According to the diagnostic criteria of coronary heart disease and the diagnostic;riteria of AS syndrome,40 patients with AS of kidney deficiency and blood stasis syndrome were selected and divided into study group and control group andomly(n=40).The control group was given conventional western medicine treatment:vspirin O.lg,once a day,atorvastatin 20 mg orally,once a night.On the basis of;onventional western medicine treatment,the study group was treated with compound anqi particles.Drug composition: sanqi 4g,hawthorn 10 g,Salvia miltiorrhiza 10 g,Zadix 10 g,Ganoderma 12 g,water decoction,one dose daily,two times a day.The two groups were treated for 12 weeks.Before and after treatment were observed in two groups of patients with clinical symptoms,AS syndromes,CAVI?ABI levels,The change of the carotid intima-media thickness;.The data were analyzed by SPSS17.0 statistical software.Result:1.The team before and after treatment comparison: after treatment serum levels of CAVI ? ABI were significantly lower,carotid intima-media thickness decreases,and relieve clinical symptoms,the doctor of traditional Chinese medicine symptom integral decreased,compared with before treatment there was a significant statistical significancedifference(P<0.01).2.The control group before and after treatment comparison: after treatment serum levels of CAVI?ABI were significantly lower,carotid intima-media thickness decreases,and relieve clinical symptoms,the doctor of traditional Chinese medicine symptomintegral decreased,compared with before treatment there was a significant statistical significancedifference(P<0.01).3.The research group compared with the control group after treatment,after treatmentserum CAVI and ABI levels drop degree of theteam are better than that of control group(P<0.05);Two groups of carotid intima-media thickness are falling,the team fell more obvious(P<0.05);two groups of clinical symptoms were improved aftertreatment,the degree of group than the control group improved more significantly(P<0.01);degree of symptom integral aspect of traditional Chinese medicine group than the control group to reduce(P<0.01).4.Comparison of blood routine,liver and kidney function,blood coagulation indexesbefore and after treatment,there were no significant differences(P>0.05);Patients did not appear due to adverse drug reactions.Conclusion:1.The compound particles notoginseng can obviously reduce CAVI and ABI patients with atherosclerosis,inflammatory.2.Compound notoginseng particles to improve the mechanism of action of atherosclerosis in patients with clinical symptoms may be related to itsantiinflame-matory,lipid and stable plaques.