| Background:The incidence of gastric polyps has increased in recent years.Gastric polyps are precancerous lesions of gastric cancer.The specific risk factors for gastric polyps are unclear.Domestic and foreign literature reports relate to diet and lifestyle habits.Gastric polyps and diets and living habits in Yangzhou are still relevant.No research report.Objective:To explore the effects of endoscopic characteristics,population characteristics,living habits and eating habits of gastric polyps on the occurrence of gastric polyps by analyzing the clinical data of patients with gastric polyps diagnosed in the SuBei Hospital.We aim to discovery of risk factors of gastric polyps can increase the understanding in physicians and populations,which provides new directions to better prevention and treatment of stomach malignancies induced by gastric polyps.Methods:Patients with gastric polyps diagnosed by gastroscopy and gastric biopsy from September 2014 to August 2015 in Electronic Gastroscopy Department,SuBei Hospital were selected.A total of 153 subjects(hereditary polyposis,P-J syndrome and other special types of gastric polyps were excluded).Meanwhile,subjects who had normal results of gastroscopy and were gender-and age-matched(with a difference of<3 years)in the same period were selected as the control group.Through the form of questionnaire survey,we retrospectively analyzed the statistical characteristics of gastric polyps,examination results of upper gastrointestinal endoscopy,living habits and eating habits between the two groups.The data were compiled by Excel and SPSS 16.0 was used for statistical analysis to find relevant risk factors affecting the occurrence and development of gastric polyps.Results:1.A total of 153 patients with gastric polyps were enrolled,of which female patients were significantly more than male patients with the ratio of male:female=1:1.94.We found that people with 40-69 years were the most frequently affected by gastric polyps,with the average age of 55.00± 11.89 years.The incidence of gastric polyps has been increased in Yangzhou in the past six years.2.A total of 305 gastric polyps were found.Pedicles were frequently seen in the basal part of the gastric polyps.There were 153(50.16%)gastric polyps with pedicles,48(15.74%)without pedicles,and 104(34.10%)with subpedicles.We considered the 2.0 cm in diameter of gastric polyps as the median level,and there were 292(95.74%)gastric polyps were less than 2.0 cm in diameter and 13(4.26%)were larger than 2.0 cm.Therefore,small gastric polyps were commonly seen and those larger than 2.0 cm were more often observed in sinuses ventriculi.Based on the distrubution of gastric polyps,29(9.51%)were in cardia,62(20.33%)were in fundus ventriculi,114(37.38%)were in corpora ventriculi,5(1.64%)were in angular notch and 95(31.15%)were in sinuses ventriculi.Hence,sinuses ventriculi and corpora ventriculi were the major sites of gastric polyps,accounting for more than half of the total number of gastric polyps.Individual gastric polyp was frequently seen,accounting for 100 cases(65.36%).For pathological examination,the most common pathological type was hyperplastic polyps,accounting for 74.56%.3.After excluding age-and gender-related influences,we found family history was a risk factor for the occurrence of gastric polyps(?2?22.643,p<0.05).There was no significant difference in BMI between the gastric polyps group and the control group(p>0.05).There are no significant differences in rice,flour,white meat,dairy products and animal viscera?between?the gastric polyps group and the control group(p>0.05).However,there were significant differences in red meat,fresh vegetables,fruits,soy products and eggs between the two groups(all p<0.05).4.After excluding age-and gender-related influences,we found no significant differences in salted food,alcohol and tea between the gastric polyps group and the control group(p>0.05).However,there were significant differences in pepper,edible oil,mental stress and smoking(all p<0.05).5.Multivariate logistic regression analysis was conducted in family history,eating habits(red meat,fresh vegetables,fruits,soy products and eggs)and lifestyle habits(pepper,edible oil,stress and smoking).After excluding confounding factors,it is concluded that family history OR is 1.571(1.023?2.414),red meat OR is 1.276(1.034?1.573),edible oil OR is 1.276(1.027?1.587)and mental stress OR is 1.266(1.044?1.537)were the risk factors of gastric polyps.Compared with domestic and foreign data,this data shows that the occurrence of gastric polyps in Yangzhou has a significant correlation with family history,red meat,edible oil,and anxiety.Due to lack of previous case-control data,this study failed to reflect the impact of changes in diet and lifestyle habits on gastric polyps in recent years.Conclusions:Middle-aged and elderly females were most frequently affected by gastric polyps in Yang Zhou area,and the most common pathological type was hyperplastic polyps.Sinuses ventriculi and corpora ventriculi were the major sites of gastric polyps.Besides,individual,small gastric polyps with pedicles were frequently observed.After excluding confounding factors,it is concluded that family history,red meat,edible oil and mental stress were the risk factors of gastric polyps. |
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