Professor Li Tong's Treatment Of Breast Cancer Climacteric Syndrome

This paper includes two parts:literature review and clinical study.The literature review consists of 2 parts,the first article is a review of Western medicine.It reviews the progress of Western medicine in the treatment of menopausal syndrome after endocrine therapy for breast cancer.,including:common drugs for endocrine therapy for breast cancer,breast cancer after endocrine treatment common adverse reactions,the mechanism,clinical manifestation and prevention and treatment of climacteric syndrome.Under the influence of many factors such as heredity,environment and so on,the incidence of breast cancer is increasing year by year.Now it has become the first place of malignant tumor morbidity and mortality that threatens women's life and health.About 50%to 70%of the patients with breast cancer are hormone dependent and need endocrine therapy.Endocrine therapy is to change the internal environment needed for the growth of hormone dependent breast cancer by blocking the synthesis of estrogen,lowering the level of estrogen and the activity of hormone receptor,so as to inhibit the malignant proliferation of tumor cells in order to alleviate the cancer.Endocrine therapy,such as chemotherapy,radiotherapy and targeted therapy,has the advantages of low price,good acceptance and high compliance.It has been widely used in clinical practice as a first-line treatment,but the side reaction of the drug itself has been gradually revealed for up to 5?10 years.Among them,the incidence of menopause syndrome after breast cancer endocrine therapy is high and the treatment is difficult.It is characterized by facial flush,hot sweat,irritability,menstrual disorder,vertigo and tinnitus,palpitation,insomnia,fatigue and less words.This syndrome,western medicine treatment,the light choice of symptomatic treatment,poor curative effect,the more serious symptoms of the replacement of endocrine therapy drugs,even the termination of endocrine therapy,seriously affecting the effect of endocrine therapy and prognosis of patients.The second is the review of traditional Chinese medicine.It reviews the progress of traditional Chinese medicine in the treatment of menopausal syndrome after endocrine therapy for breast cancer.It includes TCM knowledge of breast cancer,cognition and treatment based on syndrome differentiation.Referring to the literature of the last ten years,the author made a preliminary and rough classification of the existing syndrome types of the climacteric syndrome:liver qi stagnation syndrome,deficiency of the kidney yin syndrome,Chong-ren disturbance syndrome,spleen deficiency damp stagnation syndrome,and nutritive Qi and defensive Qi disharmony syndrome.In addition to the effective treatment of internal medicine,the external treatment of Chinese medicine has also proved to be able to effectively control the symptoms of hot flashes,sweats and perspiration caused by endocrine therapy for breast cancer,without side effects,including long-term umbilical cord application and acupuncture.Because doctors have different opinions on this disease,their treatment ideas are different.We still need further exploration and exploration.The second part is clinical study.Professor Li Tong,who has been engaged in cancer clinical work for more than 20 years,has a rich experience in the treatment of malignant tumors,and has a unique understanding of the treatment of cancer related diseases.This subject is intended to sum up professor Li Tong's medication rule in the treatment of climacteric climacteric syndrome after the treatment of endocrine therapy for breast cancer.A total of 187 patients and 600 prescriptions involving 152 drugs,including the properties,taste,meridian,efficacy and the degree of interrelated rules,are collected.To summarize professor Li Tong's basic prescription and treatment of menopausal syndrome after endocrine therapy for breast cancer,and to refine professor Li Tong's basic thought of treatment.[Objective]To summarize the rule of Professor Li Tong's treatment of menopause syndrome after the treatment of breast cancer endocrine therapy,the thought of Professor Li Tong's treatment was abstracted to provide evidence and reference for the treatment of menopause syndrome in Chinese medicine.[Methods]The spss22.0 software package is used to analyze the numerical data,and the distribution features and types of the data are revealed.With the aid of distributed computing framework spark and machine learning component mllib,data mining is realized based on FP-growth algorithm.[Conclusion]Professor Li Tong's basic prescription for treating climacteric syndrome after endocrine therapy for breast cancer and its application and treatment of climacteric syndrome:soothing the liver and regulating the flow of vital energy and remove obstruction toit;supplementing the liver and kidney,nourishing yin and reducing fire;strengthening the body resistance and eliminating evil;especially paying attention to spleen;activating blood and promoting water,and advocating transforming sweet and cold to yin.