Study On The Relationship Between Serum Uric Acid Level And Triglyceride In Middle-Aged And Elderly Population In Hotan District Of Xinjiang

Objective:To investigate the relationship between uric acid(UA)and triglyceride(TG)in Uygur middle-aged and elderly people in Hotan district of Xinjiang.Methods : Stratified sampling and complete randomization were used to select 1356long-term residents aged over 40 in Hotan District of Xinjiang.The subjects were divided into two groups according to gender,then according to the diagnostic criteria of hyperuricemia,each group were divided into UA normal group and high UA group,finally,based on the three percentile of UA normal groups,they were divided into three layers,thus forming four layer with different UA levels.Single factor analysis and multivariate Logistics regression analysis were used to investigate the relationship between UA level and TG.Results:UA levels were positively correlated with TG in the general population(r =0.165,P <0.001),and there was a gender difference in the correlation with other indexes.Single factor analysis of UA and TG showed that:There were significant differences in TG levels between UA layers of different genders(P<0.001).With the increase of UA level,the level of TG in male and female increased,and the prevalence of triglyceride were also increased,all of which were statistically significant(P < 0.001).The results of hypertriglyceridemia and uric acid Logistics regression analysis showed that Compared with the first layer,the probability of second,third,fourth layer suffering from hypertriglyceridemia increased by 1.004 times,1.203 times,2.061 times respectively in female group.In male group,the probability of third,fourth layer suffering from hypertriglyceridemia increased by 0.809 times and 4.232 times respectively Compared with the first layer,and the difference was statistically significant(P < 0.05),However,Prevalence between the first and second layers In malegroup was not statistically significant.These findings suggest that UA is independently associated with hypertriglyceridemia,and this phenomenon is prominent in women.Conclusions : There is a correlation between UA and TG in Uygur middle-aged and elderly people in Hotan district of Xinjiang.With the increase of UA level,the risk of hypertriglyceridemia is increased.The prevention of hyperuricemia and enhancement of comprehensive prevention and control of risk factors will reduce the prevalance of hypertriglyceridemia and reduce the incidence of cardiovascular and cerebrovascular disease.