| Since the birth of Moore’s Law, the semiconductor technology has been developing in accordance with the law for half a century. In 2013, the ITRS(International Technology Roadmap for Semiconductors) predicts that the semiconductor device’s feature size will reach to 7nm. With the scaling-down of device, when the electric field of the gate oxide is higher than 6MV/cm, P-MOSFET negative bias temperature instability(NBTI, Negative Bias Temperature Instability) becomes the dominant factor which limit nano devices and the life of ICs.This dissertation is based on reaction-diffusion model(RD model, Reaction Diffusion model) of NBTI, and the main works is as follows:1. The traditional analog circuit simulation design flow based on SPICE is improved to adapted to the nanometer process, so the ability of circuits’anti-NBTI degradation can be improved;2. The simple current mirror, cascade current mirror and wide-swing current mirror biasing circuit are simulated and analyzed based on RD model. The results shows that the NBTI degradation of Cascode circuit is the most serious;3. All types of single-stage amplifiers, differential amplifiers and operational amplifiers are simulated and analyzed. What’s more, the two-stage operational amplifier is improved based on analog circuit simulation design flow. And the degradation of the -3dB band width decreased from 27% to 1%, the NBTI degradation of the PSRR and SR decreased to less than 1% too, thereby the impact of NBTI degradation on the two-stage operational amplifier is reduced significantly. |