The Effection Of Auricular Plaster Therapy On Blood Pressure Of Patients With Ischemic Stroke At Convalescent Stage

Objective:To explore the influence of auricular plaster therapy on blood pressure regulation of patients with ischemic stroke at convalescent stage; Through monitoring the changes of blood pressure, hypersensitive High-sensitive C-reactive protein (Hs-CRP) and endothelin (ET-1) before and after the intervention, in order to provide objective basis for external treatment of traditional Chinese medicine for hypertension of patients with ischemic stroke.Methods:70 patients with ischemic stroke and hypertension at convalescent stage were selected from Acupuncture Department of Quanzhou Traditional Chinese Medicine Hospital (Fujian) between July 2014 and June 2015. The patients were divided into the observation group (n=35) and the control group (n=35) according to the table of random numbers. The control group was given conventional antihypertensive scheme and clinical nursing, and the observation group was given auricular plaster therapy on the basis of the treatments of the control group. The main points for auricular plaster therapy include:anti-hypertensive point, shenmen point, heart point, sub-cortical point and liver point. The therapy was given 3 times every day. at 7:00.11:00 and 17:00. respectively. At each time, every acupoint was given 15 compressions, with each lasting 4 seconds. Every 5 days formed a course of treatment, with 2 day-interval between 2 courses. The patients were given a total of 4 courses of the treatment. In each group, it was compared in blood pressure changing and every 3-days changing of fluctuation amplitude before and after the intervention. And the two groups were compared in total effective rate and significantly effective rate. And the changes of Hs-CRP and endothelin (ET-1) before and after the intervention were monitored.Results:1. A total of 70 cases were included, which 63 cases completed the experiment and 7 cases were lost (4 cases in the intervention group. and 3 cases in the control group).2. Baseline comparison:there were no statistically significant differences between two groups in gender, age. Body Mass Index BM1). education, course of the disease, hypertension level, medication use. complications(dyslipidemia and diabetes). Neurologic impairment score (NIHSS). lifestyle (smoking, drinking, light diet), etc.. (P>0.05). however, the data were comparable. There were no statistically significant differences between two groups in systolic pressure, diastolic pressure and daily fluctuation amplitude before intervention (P>0.05), but the data were comparable; There were no statistically significant differences between two groups in hs-CRP and ET-1 before intervention (P>0.05).3. Blood pressure:the systolic pressure and diastolic pressure of both groups were decreased after intervention, and the differences were of statistical significance (P<0.01); The systolic blood pressure and diastolic blood pressure in the observation group were significantly higher than those in the control group (P<0.01):The daily fluctuations in systolic blood pressure and diastolic blood pressure were lower than those before intervention, the difference was statistically significant (P<0.01). The diurnal systolic blood pressure fluctuation in the intervention group was significantly lower than that in the control group (P < 0.01); and no significant differences in the diastolic pressure (P>0.05). Fluctuation amplitudes of every 4-day systolic pressure and diastolic pressure were drawn into the graph, indicating that the amplitude of systolic blood pressure fluctuation in the observation group was higher than that in the control group.4. Hs-CRP:There were statistically significant differences in comparison of pre-intervention and post-intervention hs-CRP in each of the two groups (P<0.01). and there were statistically significant differences between two groups in hs-CRP after intervention (P<0.05).5. ET-1:There were statistically significant differences in comparison of pre-intervention and post-intervention ET-1 in each of the two groups (P<0.01). and there were statistically significant differences between two groups in ET-1 after intervention (P<0.05).Conclusion:Auricular plaster therapy can effectively reduce the systolic blood pressure and diastolic blood pressure of the patients with ischemic stroke and hypertension at convalescent stage, and decline the concentration of ET-1 and hs-CRP. prompting that auricular plaster therapy can improve endothelial function, and the decline of inflammatory reaction can reduce the risk of recurrence of cerebrovascular events.