Clinical Analysis Of 188 Cases Of Bronchial Pneumonia With Lobe Or Multi Foci Infiltration In Children

Objectives:Lesions of this study is based on the analysis of major changes of bronchial pneumonia clinical characteristics, etiology, imaging findings and treatment outcome, aimed at improving clinicians about bronchopneumonia with lobe or multi foci infiltration, knowledge level。Methods:Collect 188 paediatric bronchopneumonia cases, with lobe or multi foci infiltration, presenting in the Children’s Hospital Affiliated to Soochow University between May 2012 and April 2013,including clinical symptoms, signs, etiology characteristics and treatment outcome.All data using SPSS 18.0 statistical software for statistical analysis。Results:In 188 cases, 106 cases are male(57.0%), 82 cases are female(43.0%). The youngest patient is 1 day and eight hours newborns, while the oldest 14-year-old.Participants are categorized according to age accordance with CAP guidelines, there are 22 cases(male 18 cases, female 4 cases) in the <6 months group, 45 cases(male 30 cases, 15 cases) in 6 months to 2 years group,55 cases(male 21 cases, female 34 cases) in 2-5 years group, and 66 cases in > 5 years group.There are 147 cases of fever, 187 cases of cough and 30 cases of wheezing; X-ray examination:37 cases with bilateral lesions, 104 cases are on the right side, 47 cases are on the left side, pleural effusion is finded in 7 cases.Laboratory examinations: there are 54 cases with WBC increasing; while 9 cases reducing, 125 cases normal. CRP are not detected in 11 cases, the remaining 177 cases were performed CRP detection, among which 109 were elevated CRP.Etiology:mycoplasma infected in 104 cases, Staphylococcus aureus infection in 3 cases, 22 cases with streptococcus pneumoniae infection, Haemophilus influenzae infected in 5 cases, 34 cases with virus infection(21 cases with adenovirus, 9 cases with syncytial virus and parainfluenza III in 2 cases, 1 case with influenza type A, type B influenza virus in 1 case), did not detect any pathogens in 62 cases.(The mixed infection of Mycoplasma and bacteria are 17 cases, including staphylococcus aureus, 2 cases with streptococcus pneumoniae, 3 cases with haemophilus influenzae, 12 cases with streptococcus pneumoniae, the mixed infection of Mycoplasma and virus are 26 cases, 19 cases with adenovirus, 4 cases with syncytial virus, 1 cases of influenza type A, type B influenza virus type in 1 case and parainfluenza 3 in 1 case). The 188 cases are recovered after systematic treatment.There are no death and the prognosis is good。Conclusions : 1. More than 2 years of age is the highest-incidence age for bronchopneumonia with lobe or multi foci infiltration in children;2. The pathogen species of bronchopneumonia with lobe or multi foci infiltration in different age groups are not the same:children under two years of age are almost infected with the virus, especially the adenovirus;over two years old children are mycoplasma pneumonia infection;while bacterial infections with Streptococcus pneumoniae have no difference in age;3. Besides the common clinical manifestations of bronchopneumonia,bronchopneumonia with lobe or multi foci infiltration in different age groups have different characteristics: children under the age of two merged wheezing and hyperpyrexia more easily,more than two years old children appear more moderate fever, and thermal process much longer;4. Bronchopneumonia with lobe or multi foci infiltration in children < 2 years old appear increasing of white blood cell count、lymphocyte percentage、 platelet count and the myocardial enzymes, while > 2 years old children appear many neutrophils, elevated CRP.5. X-ray examination is not a clear distinction with pneumonia pathogens in children with lobe or multi foci infiltration of bronchopneumonia.