Study On The TCM Syndrome Characteristics And Related Factors In Female Patients Of Perimenopausal Syndrome And Cervical Spondylosis

ObjectiveAccording to epidemiological investigation, this study collected the menopausal transition of cervical spondylosis patients. Mainly four diagnostic data of traditional Chinese medicine, this paper discusses the distribution regularity of TCM symptoms and syndrome factors, this provides a basis for the TCM clinical syndrome differentiation and treatment of the disease; and discusses the relationships between TCM symptoms of perimenopausal syndrome and cervical spondylosis and pathogenic factors of cervical spondylosis, easy to guide the treatment of the disease, also provide convenience for clinical treatment.MethodsBy using clinical survey method, this study base on DME rules, it investigated the TCM symptoms of perimenopausal syndrome and cervical spondylosis, pathogenic factors of cervical spondylosis of who into this study. Through analyzing the data, in order to discussing the relationships between TCM symptoms of perimenopausal syndrome and cervical spondylosis and pathogenic factors of cervical spondylosis scientifically. The study samples of patients were selected from department of orthopaedics in Guangdong Provincial Hospital of Chinese Medicine in April 2013-February 2015. The sample size is 205-410 according to estimate rule of multivariate factors analysis. It builds database by using software EPIdata3.1, after entering information of patients, it transform raw data into database of software SPSS17.0, in order to statistically sort and analyze data. Enumeration data express in constituent ratio. Measurement data express in mean number± standard deviation, min, max and median. The method of analyzing classification of diseases, TCM symptoms and influence factor is unconditioned Logistic regression analysis, factor analysis or clustering analysis; the test level sets to 0.05.Results1. The result of analyzing the data of 216 patients who have perimenopausal syndrome and cervical spondylosis shows that insomnia, dizziness, headache, chills, cold limbs, numbness, palpitations, hot flashes, sweating, etc are the main clinical symptoms of the disease. It also found the main TCM pathogenesises are blood deficiency, Yin deficiency, kidney deficiency.2. Using factor analysis method to analyze 19 TCM symptoms and signs with dimension reduction, and extracted six factors finally. Using cluster analysis for six factors and tongue, pulse condition, at the same time combined with clinical practice, it concluded 5 kinds of syndrome classification of patients with perimenopausal syndrome and cervical spondylosis are Liver Depression and Qi-stagnated Blood Stasis syndrome, Kidney-Yang deficiency syndrome, Qi and Blood deficiency syndrome, Kidney-Yin deficiency, Liver and Kidney deficiency syndrome.3. The result of analyzing between TCM symptoms and syndrome factors by using single factor analysis and Logistic regression analysis shows that, age, occupation, neck injury history, stiff neck, myopia, hours of bent head, living habit and physical exercise have clinical significance when discriminate the TCM symptoms.ConelusionInsomnia, dizziness, headache, chills, cold limbs, numbness, palpitations, hot flashes, sweating, etc are the main clinical symptoms of the patients with perimenopausal syndrome and cervical spondylosis. It concluded 5 kinds of TCM syndromes which are Liver Depression and Qi-stagnated Blood Stasis syndrome, Kidney-Yang deficiency syndrome, Qi and Blood deficiency syndrome, Kidney-Yin deficiency, Liver and Kidney deficiency syndrome. The relationship between TCM syndrome characteristics and related factors has been confirmed. For the clinical diagnosis and treatment providing a basis. Meantime, the study on standardization of TCM syndrome made beneficial attempt.