The Clinical Curative Effect Observation Of "Xingsu Erchen" Decoction Treatment To Acute Exacerbation (Wind-cold Type) Of Chronic Bronchitis

Objective: Xingsu Erchen Decoction has the effect of ventilating lung, dispellingcold, and expectorant, anti-tussive, relieving asthma. The aim is to test the effect ofXingsu Erchen decoction on the treatment of Acute Exacerbation (Wind-cold Type) ofChronic Bronchitis.Methods: Using a randomized grouping study to equally divide82patients intotreatment group and control group randomly. The treatment group was given XingsuErchen decoction (cassia twig20g, preparde ephedrae herba15g, perillae stem10g,armeniacae semen amarum10g, asari radix et rhizoma6g,pericarpium citrireticulatae10g,poria15g, rhizoma pinellinae praeparata15g,adenophorae radix15g,ophiopogonis radix15g, prepared polygalae radix10g, prepared farfarae flos15g,platycodonis radix10g, caryophylli flos10g, acori tatarinowii rhizoma10g, fructusziziphi jujubae10g, glycyrrhizae radix et rhizoma10g, fresh ginger20g). We usedTCM extracting machine to decoct Xingsu Erchen decoction in boiling room ofYunnan College of Traditional Chinese Medicine, and divided each medicinalpreparation into three200ml bags, telling the patients of treatment group take a warmbag three times a day after eating for half an hour. The control group was given coughpill(made by Tradition Chinese factroy of Kunming) and it was taken six cough pillstwice a day. One course of treatment was two weeks by two groups. Compared thefinal aggregate score, clinical symptoms,signs and therapeutic effect assessment indexof two groups,at the same time, consulted “Chinese herbal medicine new medicineclinical research principles” made the evaluation of the clinical therapeutic effect. We obtained conclusion through statistical results.Results: We planed to investigate78cases, actually investigated82cases, whichincluded41cases of treatment group and41cases of control group. Among theinvestigation,1case did not conform to the treatment,1cases did not complete thetreatment(see Table1).82cases of all analysis collected works,80cases were fit forprotocol set, and80cases were security data set. In fact, there were only40cases ofthe treatment group and40cases of the control group. Compared the effective rate oftwo groups, the difference has statistically significant (p<0.05), and compared clinicalcontrol efficiency with obvious efficiency, the difference has also statisticallysignificant (p<0.05). Two groups of patients with symptom and physical sign wereimproved. The variance between the aggregate scores of symptom and physical signwas statistically significant(P＜0.05). Improvement of symptom and decline ofintegration in treatment group is better than these of control group. In the two-weekperiod, the improvement of chest X-ray, tongue-appearances and pulse conditionswere obvious. And blood routine, urinalysis, excrement routine, liver function andrenal function were no serious abnormalities around the treatment.Conclusion: Xingsu Erchen decoction had the effect of ventilating lung, dispellingcold, and expectorant, anti-tussive, relieving asthma. And it could clearly control andimprove the symptom of Acute Exacerbation (Wind-cold Type) of Chronic Bronchitis.Not only that, it had no obvious toxic and side effects. Based on this research, wedraw the conclusion: Xingsu Erchen decoction could be selected as the clinicalmedication of Acute Exacerbation (Wind-cold Type) of Chronic Bronchitis.