Arthroscopic Debridement Combined With Uygur Maizhuni Treatment Of Knee Osteoarthritis Randomized Controlled Trials

Objective: To observe the clinical efficacy of Uygur maizhuni combined witharthroscopic debridement treatment as early as the mid knee osteoarthritis and surgerybefore and after the medication in patients with synovial fluid and serum expression ofMMP-1,3,13and TIMP-1and IL-1the level of determination of Uygur maizhunitreatment as early as in advanced knee osteoarthritis may be the mechanism. Methods:90cases of patients with knee osteoarthritis were randomly divided into experimental groupand control group,45cases in each group.The experimental group in arthroscopic kneeclean up with3days after Uygur maizhuni treatment control group to be after three daysof placebo,4,8and12weeks after surgery, symptoms, signs integral, the VAS, as thevalue of law and security indicators to assess and detected before surgery and12weeksafter surgery in patients with synovial fluid and serum of MMP-1,3,13and TIMP-1andIL-1level. Results: Postoperative efficacy of12weeks and found that the experimentalgroup total effective rate was97.8%, the total effective rate of80.0%,93.3%of the totaleffective rate of the control group, the total effective rate was57.8%, statisticallysignificant differences between the two groups(P <0.05) after the end of the treatment, theserum MMP-3, TIMP-1in serum and synovial fluid with the control group after thetreatment group compared to the difference was statistically significant (P<0.05).Conclusion: Compared with simple arthroscopic debridement, the arthroscopewith the dimension drugs buy Uygur maizhuni treatment of early osteoarthritis of the kneeof the medium-term efficacy is more significant, especially for patients with swollen joints,pain, joint activity, playing soft legs and other symptoms and signs improved significantly,but its mechanism of action and long-term efficacy remains to be further experimentalstudies and clinical observations to verify and prove.