"Qingre Jiedulishi Formula Combine Otopoint" Treat The Syndrome Of Acne Vulgaris Of Damp-heat Of Lung And Stomach Clinical Observation

ObjectiveObserve the clinic efficacy and security of "Qingre jiedulishi formula combine Otopoint treatment" treatment on the syndrome of acne vulgar is of damp-heat of Lung and stomach Syndrome.MethodsChoose our 2009 May-December 2010 outpatient service of acne vulgaris of damp-heat of Lung and stomach Syndrome 80 cases were randomly divided into the treatment group (50 cases) and control group (30 cases). The treatment group were taking Qingrejiedulishi formula twice one day for 42 days and doing otopoint treatment twice one week. Internal and external treatment,2 weeks for a course, laparoscope six weeks. The control group were taking Danshentong Capsules three times everyday and smearing 0.3% Viaminate and Vitamin E Cream twice one day for 42 days.2 weeks for a course, use continuously 6 weeks. The patients were observed in the first and second week after treatment,4 weeks,6 weeks respectively, record the complete observation form inflammatory lesions (comedones and hoary head acne) and inflammatory lesions (pimples, pustular and nodule) and the number of total. Ask medication adherence, a record adverse reactions. Take notes of adverse reactions Clinical criteria reference to the efficacy criteria on " efficacy criteria and grading standard of acne vulgaris" instituted by Chinese Medical Association dermatology and cosmetology group Oct.1997. According to the treatment of the first 2 weeks,4 weeks, the first six weeks ago after lesions calculated curative effect index number counting, and based on comprehensive effect assessment standard therapeutic evaluation, According to the inflammatory lesions, the number of inflammatory lesions changes, observation treatment group, the control group of two kinds of lesions influence. Every two weeks for a curative effect evaluation and comparison. Meanwhile, according to the group, compared with patients during the study, new appearance or aggravate symptoms, signs and disease, safety evaluation.ResultQingre jiedulishi formula combine Otopoint treat the syndrome of Acne vulgaris of Damp-heat of Lung and Stomach certificate of significant efficiency for 17.39%, efficient 78.26%, with the total effective rate of 95.65% with control group for the significant efficiency 14.29%, efficient 71.26%, with the total effective rate of 85.71%. The chi-square test between the two groups curative effect, there are no significant difference (P> 0.05).There is a significant difference between the treatment group and control group of the therapeutic index after 6 weeks. The safety indicators show the Qingre Jiedulishi formula combine Otopoint treatment on the syndrome of acne vulgaris of damp-heat of lung and stomach syndrome is safety. Conclusion1. The Qingre Jiedulishi formula combine Otopoint treatment had definite effect, it can well improve patients with phlogistic type and non phlogistic type lesions.2. From the therapeutic index, The Qingre Jiedulishi formula combine Otopoint treatment formula is superior to the control group. At the same time, The Qingre Jiedulishi formula combine Otopoint treatment formula is safety.