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To Purge The Soup Intestinal Transmission Influence Function In Mice Experimental Study Of

Posted on:2012-12-07Degree:MasterType:Thesis
Country:ChinaCandidate:Z G WangFull Text:PDF
GTID:2214330338462180Subject:Traditional surgery
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Purpose: Combination of literature research and teacher experience in the clinical treatment of constipation, laxative as the main rule to law, the use of self laxative side group side, the experimental study of normal mice to investigate the laxative and the Self-pass method Have side effects of treatment of functional constipation, the party for the treatment of chronic functional constipation to provide a scientific basis.Method: Select normal mice to observe the object, given orally self laxative side, both through oral constipation as positive control and distilled water as control, was observed in mice fed the first row of melena after time, fecal total grains, Melena grains and intestinal propulsion rate, compared among the three groups were observed on mice self defecation purge function.Result: The experimental group compared with the control group, the first row of black mice was significantly shorter then (p <0.01), total grain number increased fecal (p <0.01), black grains will also increase (p <0.05), positive control group and the experimental group, the experimental group were shortened first defecation (p <0.05), black grains have also increased (p <0.05), total grain number feces showed no abnormal (p> 0.05), that self-pass Tom will be able to increase the peristalsis, normal mice have a stronger role in promoting bowel movement. The experimental group compared with the control group, significantly higher rates of intestinal advance (p <0.01), that self purge soup can promote intestinal peristalsis, the normal mice significantly promoted intestinal movement, the control group and compared with the control group, forward rate increased intestinal (p <0.05), is illustrated through oral constipation can also promote intestinal peristalsis, the normal mice can promote bowel movement, the experimental group and control group, Intestinal propulsion rate also increased (p <0.05), that intends to purge from normal mice Tang role in promoting bowel movements Constipation oral than obvious.Conclusion: Clinical application of self purge soup for years, its effect is significant. In order to affirm its laxative effect, we further observed in animals from mice to be laxative soup bowel function and promote intestinal function. In this study, attending functions and under the observation of its effect on normal defecation in mice, experimental results show that normal mice can only shorten it time to first black to increase the total grain number and melena stool grains. Self purge soup that normal mice can increase the intestinal peristalsis, there is a strong role in promoting bowel movement. Since then, Tom was self purge promote normal function of intestinal research, the findings show that can only promote intestinal peristalsis, the normal intestinal movement in mice significantly promoted the same time, research also shows that from normal mice to be laxative soup promote bowel movement than Constipation oral obvious. The small intestine dysfunction, slow, slow intestinal motility of chronic functional constipation is the main pathological mechanism. This shows good self purge Tang Youliang the role of promoting bowel movement.Large number of clinical practice and animal studies have shown that self treating functional constipation laxative is effective. Through this project the research, observation and verification of self Mice catharsis soup enhanced bowel function and promote the role of defecation in mice for further study of "law laxative" effect of the treatment of functional constipation and validation of their safety and effectiveness of the foundation.
Keywords/Search Tags:Self purge soup, intestinal transit function, Experimental study, constipation
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