The Evaluation Of Exercise Tolerance Of Rate Responsive Pacemaker In Sick Sinus Symptom Patients With Angina Pectoris

Objective: To observe the clinical effect and evaluate the exercise tolerance in sick sinus symptom patients with angina pectoris after implanting rate responsive pacemaker (DDDR). Methods: 12 patients were implanted the rate responsive pacemaker(DDDR). all had been diagnosed as sick sinus symptom accompanied with angina pectoris through former history of myocardial infarction or angina pectoris, a coronary artery radiography, the transesophageal atrial pacing and Holter records. Pacemakers were programmed without responsive demand mode(DDD), and then programmed with it after 6 months later(DDDR). Comparing exercise duration, maximal heart rate carrying on treadmill test, the number of reversible cardial ischemic segment in three projections: minor axis, level macroaxis, vertical macroaxis through ^99mTc- MIBI myocardial perfusion imaging under exercise load during each pace mode. Meanwhile recording frequency and duration of daily anginal attacks, the amount of nitroglycerine per week used for relief of chest pain during each pacing mode. Results: Compared with DDD mode, mean exercise duration and maximal heart rate showed an increase during DDDR mode(P<0.05), however, frequency and duration of anginal attacks, the amount of nitroglycerine per week had no increase(P>0.05). No statistical difference was found in myocardial perfusion imaging under exercise load (P>0.05). Conclusions: Rate responsive pacemaker...