| Drug management for cancer pain is the pharmacy administration. Study focus onthe methods of scientific, effective, reasonable, and standard analgesic drugapplicationThis study included three parts1. Study on standard method and impact oneffectiveness of quality of life, physical and psychological activities.208cases wereobserved, including the quality of life psychiatric symptoms including depressionanxiety insomnia and suicidal tendencies physiological symptoms including weightappetite and physical strength.The results showed that the average of visual analogscale (VAS) for the quantitative analysis of analgesic score was8.4±2.5and8.5±3.1in the observation group and control group before analgesia, and2.8±1.7and7.8±3.6after analgesia; the body weight was increased, unchanged, and decreased was70.8%,11.2%,18.1%and18.8%,25.0%56.2%of patients in the observation andcontrol group, respectively; the appetite was improved in60.4%and14.1%for theobservation and control group; the fatigue alleviate was28.1%and4.7%, respectively;the average score of quality of life was30.6±7.9and31.2±11.4, and46.5±10.6and34.7±15.4in the observation and control group before and after analgesia;33.7%ofall patients presented with manifestations of depression before and only23.5%afteranalgesia;20.8%of patients in the observation group met the diagnostic criteria ofdepression before and9.7%after analgesia;24.0%of all patients presented withsymptoms of anxiety before and only13.9%after analgesia;22.9%of patients in theobservation group presented with anxiety before and9.4%after analgesia;28.1%ofpatients in the control group presented with anxiety before and25.0%after analgesia;the sleep status was improved in19.2%of all patients,36.1%in the observation and12.5%in the control group; Analgesia can improve the quality of life of patients withcancer, alleviate depression, anxiety, sleep disorders, suicidal tendencies, andincrease appetite and body weight; there was significant difference between the twogroups. The study proposes is that the application of analgesic drug for cancer is aspecial subject in pharmacy administration.2. By using multi-center clinical investigation study the current situation ofanalgesic drug application for cancer pain1000patients of cancer pain were investigated in five Cancer Centers. The results showed that those patients with standardized application of analgesia (three steps,timing, quantitative) accounted only29.5%of investigated cases, and those withnon-normative analgesia (based on patients symptoms) accounted for70.5%. the totaleffective rate were97.6%and81.7%for standardized and non-normative treatmentgroup; the significant effective rate were89.2%and32.8%for standardized andnon-normative treatment group with statistical significance; there was no statisticallysignificant differences between two groups about treatment cost. We conclude that astandard treatment program is more effective for cancer pain relief and propose thebest drug management programs for cancer pain control.3. Establish a cancer pain animal model the animals were divided into two groups,one given analgesic drugs and the others as control. By an observation of appetite,body weight tumor growth and survival time. Study confirmed that pain control cansignificantly improve the animal appetite maintain or increase body weight inhibittumor growth, and prolong the survival time.Study confirmed that the cancer pain control and rational drug management hasthe social and clinical significances. the pharmacy administration and managementstrategy play an very important role in cancer pain medication. |
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