The Study Of The Intervention Effecte Of Moxibustion Zusanli Fenglong On Hyperlipidemic Rat Model And Clinical Validation

ObjectiveMining the basis of the traditional Chinese medicine theory, after induction and consolidation, under the guidance of the classical theory that including" the stomach and the spleen are acquired","spleen governs the transportation","the spleen is the source of phlegm", and constantly deepen the understanding of the etiology and pathogenesis of hyperlipidemia. We believe that:elevated blood lipids belong to the scope of TCM invisible sputum, lesions in the spleen and stomach two dirty,virtual Spleen-based,real phlegm stagnation as the standard.In this study, the first observation of the moxibustion Zusanli point, the moxibustion Fenglong point,the moxibustion Zusanli together Fenglong point on serum lipids of hyperlipidemic model,then the animal experiments of the results of use in the clinical,observation Observe whether the animal studies and clinical research makes a difference.MethodsThe first part of this paper is a literature study on hyperlipidemia on the understanding and treatment of modern medicine and the tradition medicine hyperlipidemia, and clinical problems encountered, highlighting the advantages of acupuncture in this respect.In the second part of the animal studies, SD rats60, male and female in half, fed with normal diet after2days according to body weight according to the random number table, the rats were randomly divided into the blank control group of8, the model control group of10, the Zusanli group Of13, the Fenglong of14, the Zusanli together Fenglong group of13. the High fat diet model group, the Zusanli group, the Fenglong group, Zusanli together Fenglong group, four weeks after the detection of serological markers in each group to determine the model was successful,and then in the next eight weeks,fed with normal diet, the treatment group received moxibustion related points,just crawl animal model control group without treatment, to observe moxibustion at Zusanli, moxibustion Leong, moxibustion Zusanli together Fenglong the hyperlipidemic disease model of serum lipids and hemorheology.In the third section, first select the75patients with hyperlipidemia, randomized25cases assigned to the Zusanli group, the Fenglong group of23cases, the Zusanli together Fenglong group of27patients,after shedding nine cases,observationthe patient's serum lipids, body, changes in clinical symptoms.Results1.A rat model of blood lipids and AI levels:8weeks after the moxibustion treatment,compared with model group, the Zusanli group, the Fenglong group,Zusanli together Fenglong serum TG,TC and LDL-C level,AI Index significantly lower difference(P<0.01),HDL-C levels were significantly elevated.the Zusanli group and the Zusanli together Fenglong group have more advantages in lowering TC,the Fenglong group and the Zusanli together Fenglong group have more advantages in lowering LDL-C.2.Hemorheology:Compared with the model group, the Zusanli group, the Hong Leong group,the Zusanli together Fenglong group of high shear and low shear rate,plasma viscosity,hematocrit,erythrocyte electrophoresis time, erythrocyte aggregation index were significantly decreased,the difference was significant.3.Clinical lipid levels in patients with:the Zusanli group, the Hong Leong group, the Zusanli together Fenglong group can be lowering blood pressure,which together Hong Leong group Zusanli more effective4.Body of clinical patients:no significant change after treatment,three groups of patients with body size.5.clinical symptoms points:the Zusanli group, the Fenglong group, the Zusanli together Fenglong group can be effective to reduce the symptom score of patients with hyperlipidemia, in which the Zusanli together Fenglong group more effective.Conclusion1.the moxibustion Zusanli point,Fenglong point,Zusanli together Fenglong point,and hyperlipidemia model rats can effectively reduce serum TC, TG and LDL-C,AI index,elevated HDL-C.2.Moxibustion at Zusanli point, Zusanli together Fenglong point significantly reduce hyperlipidemia model serum TC, the moxibustion Fenglong, Zusanli together Fenglong point in reducing hyperlipidemia model of serum LDL-C obvious.3.The moxibustion Fenglong point,Zusanli together Fenglong point,can effectively reduce the hyperlipidemia model rats hemorheological parameters.4. Moxibustion Zusanli point,Fenglong point,Zusanli together Fenglong point can be effective in treating patients with hyperlipidemia, and the combination of the two points better.5.Moxibustion Zusanli point,Fenglong point,Zusanli together Fenglong point can effectively reduce the clinical integration of the patients with hyperlipidemia, to improve the patient's clinical symptoms, and the combination of the two points better, but to improve the patients body is not obvious. 6.The basic theory of Chinese medicine as the"the stomach and the spleen are acquired","spleen governs the transportation","the spleen is the source of phlegm" certain laboratory and clinical evidence.