| This paper mainly includes twoparts:literature review and clinical research.Literature review:The research on chronic obstructive pulmonary disease(COPD)(referred to as chronic obstructive pulmonary disease)in recent years is mainly discussed from western medicine and traditional Chinese medicine.The western medicine review summarizes the research progress of chronic obstructive pulmonary disease in recent years from the definition,pathogenesis,diagnosis,treatment and management status of chronic obstructive pulmonary disease.The review of TCM expounds the research situation of TCM in recent years from the aspects of disease name,etiology and pathogenesis,TCM treatment and clinical research.Clinical ResearchObjective:To explore the long-term effect of traditional Chinese medicine on COPD.Methods:A total of 70 patients with chronic obstructive pulmonary disease were included,and they were divided into an integrated traditional Chinese and Western medicine treatment group and a Western medicine treatment group according to the patients’ wishes.The treatment group of integrated traditional Chinese and western medicine used traditional Chinese medicine on the basis of standard western medicine treatment plan,while the western medicine treatment group only used the western medicine treatment plan.Observed and followed up every 3 months to record acute exacerbation,symptom score,COPD assessment test(CAT score),6-min walking distance,modified British Medical Research Council dyspnea questionnaire(MMRC),patientreported outcome(PRO)scale score,patient satisfaction with efficacy(ESQ)score,SF-36 scale score,compliance,etc.,for a period of 2 years,the above scores and pulmonary function data were recorded after the last observation.Statistical analysis of data was performed with SPSS 23.0.Results:When entering the group,the baseline conditions of the two groups were uniform except for pulmonary function grading,PRO and ESQ scores.After two years of follow-up,1 Acute exacerbation frequency:The acute exacerbation frequency in the integrative medicine group was lower than that in the western medicine group(P<0.05).2 Frequency of cold:There was no significant difference in the frequency of cold between the integrative medicine group and the western medicine group(P>0.05).3 Pulmonary function:There was no significant change in FEV1%predicted value in the western medicine treatment group(P>0.05),and FEV1/FVC decreased slightly,but there was no statistical difference(P>0.05).The predicted value of FEV1%in the integrative medicine group was slightly increased,but there was no statistical difference(P>0.05),and there was no statistical difference in FEV1/FVC(P>0.05).There was no significant difference in FEV1%predicted value and FEV1/FVC between the two groups(P>0.05).The severity of pulmonary function:There was a statistically significant difference in the pulmonary function classification between the two groups at the time of admission(P<0.05),Two years later,the number of patients with grade 3 and 4 pulmonary function decreased and the number of patients with grade 2 increased in both groups,but there was no significant difference between the two groups and between the two groups(P>0.05).suggesting that both schemes could reduce the severity of pulmonary function,but the improvement was not obvious.Comprehensive evaluation group:integrated traditional Chinese and western medicine treatment group D,B group decreased significantly,C group,A group increased;the number of patients in group D and group B in the western medicine treatment group decreased,while the number of patients in group C and group A increased,and there was no significant difference between the two groups(P>0.05).4 Clinical symptom score and CAT score:clinical symptom score and CAT score decreased(P<0.05).Compared between the two groups,the clinical symptom score and CAT score in the integrative medicine group were significantly decreased(P<0.05).5 MMRC grading and emotional score:both MMRC grading and emotional score decreased(P<0.05).There was no significant difference between the two groups after 2 years(P>0.05).6 6 min walking distance:6 min walking distance of integrated traditional Chinese and western medicine treatment group increased(P<0.05),Western medicine treatment group had no significant change(P>0.05);comparison between the two groups:the combination of traditional Chinese and western medicine treatment group 6 min walking distance increased(P<0.05).7 PRO score:when entering the group,the PRO scores of the two groups were statistically different(P<0.05);The PRO score of the integrative medicine group was higher than that of the western medicine group.Compared before and after follow-up,PRO score in the integrative medicine treatment group was decreased(P<0.05).Western medicine treatment group had no significant change(P>0.05);there was no significant difference in PRO score between the two groups after 2 years(P>0.05).8 ESQ score:when entering the group,the ESQ scores of the two groups were statistically different(P<0.05),and the ESQ score of the integrative medicine group was higher than that of the western medicine group.Compared before and after follow-up,ESQ scores increased(P<0.05);comparison between the two groups after 2 years;Compared with the western medicine treatment group,the ESQ score of the integrative medicine treatment group was increased(P<0.05).9 Compliance comparison:Chi-square test showed no significant difference between the two groups(P>0.05).Conclusion:The integrated Chinese and Western medicine treatment program can more effectively reduce the acute exacerbation risk of patients,improve clinical symptoms,enhance exercise endurance,improve quality of life,and improve efficacy satisfaction. |