Clinical Efficacy Observation Of Jian Pi Qu Shi Warm Acupuncture In The Treatment Of Active Ankylosing Spondylitis

Objective By observing and evaluating the effectiveness and safety of Jian Pi Qu Shi warm acupuncture in the treatment of patients with active ankylosing spondylitis,to provide new ideas for the clinical treatment of active ankylosing spondylitis.MethodsSeventy patients with active ankylosing spondylitis who met the inclusion criteria were divided into a test group and a control group,35 patients each,who were treated with basic therapy,and the control group was given oral celecoxib capsules alone,1 capsule each time,2times/day,for 4 weeks.In the test group,on top of oral celecoxib capsules,was treated with Jian Pi Qu Shi warm acupuncture,twice a week,on Tuesdays and Thursdays from 15:00 to17:00,1h/time,for 4 weeks.observe the quantitative TCM evidence score grading score,condition score,ASDAS-CRP,test CRP,blood sedimentation,blood routine,liver and kidney function before and after treatment,and evaluate the safety,ASAS20 achievement rate,TCM evidence efficacy of the two groups.WPS tables were used for data entry and SPSS 20.0software was used for data analysis.ResultsA total of 70 cases were included in this trial,with no dislodged,excluded,ordiscontinued cases.1.The differences in baseline information between the two groups of patients were not statistically significant(P>0.05)and were comparable.2.Objective indicators:(1)Blood sedimentation、CRP:After treatment,blood sedimentation and CRP were lower in both groups than before(P<0.01),and the difference between the test and control groups was not statistically significant(P>0.05).(2)Disease Score:After treatment,the PGA,spinal pain,BASFI,morning stiffness,and peripheral joint swelling and pain scores in both groups were lower than before(P<0.01);after treatment,there were statistically significant differences in spinal pain(P<0.01)and BASFI(P<0.05)between the two groups;the differences were not statistically significant when comparing PGA,morning stiffness,and peripheral joint swelling and pain(P>0.05).(3)ASDAS-CRP scores:Before treatment,the ASDAS-CRP scores of both groups,the difference was not statistically significant(P>0.05);after treatment,the ASDAS-CRP scores of both groups were lower than before(P<0.01);the difference between the two groups was statistically significant(P<0.01).(4)TCM Evidence Score:Before treatment,there was no statistically significant difference between the two groups in terms of TCM evidence points(P>0.05);after treatment,the TCM evidence points in both groups improved compared with before(P<0.01);the difference between the two groups was statistically significant(P<0.01).3.Clinical efficacy:(1)ASAS20 Compliance rate:After treatment,the ASAS20 attainment rate was 82.9% in the test group and 57.1% in the control group,and the difference wasstatistically significant(P<0.05).(2)Chinese medicine evidence of efficacy:The total effective rate after treatmentwas 94.28%in the test group and 34.28% in the control group,and the difference was statistically significant(P<0.01).4.Adverse reactions:The incidence of adverse reactions was 2.86% in the test group and22.85% in the control group after treatment,and the difference was statistically significant(P<0.05).ConclusionsThe combination of Jian Pi Qu Shi warm acupuncture method with celecoxib and oral celecoxib alone was effective in improving symptoms and signs.There was no difference between the two groups in improving PGA,morning stiffness,peripheral joint swelling and pain,but the combination of Jian Pi Qu Shi warm acupuncture method with celecoxib was more effective in improving inflammatory index,spinal pain,BASFI,ASDAS-CRP score,TCM evidence score,ASAS20 efficacy evaluation,TCM evidence efficacy and gastrointestinal adverse effects.