Clinical Observation On The Treatment Of Row Warm Acupuncture Combined With Celecoxib For Ankylosing Spondylitis Of Kidney Deficiency And Du-meridian Cold Syndrome

Objective:This study observes the clinical efficacy of row warm acupuncture combined with celecoxib in the treatment of ankylosing spondylitis of kidney deficiency and du-meridian cold syndrome,and provides references and ideas for acupuncture and moxibustion in the treatment of ankylosing spondylitis of kidney-deficiency and du-meridian cold syndrome.Methods:Collected 70 patients who met the inclusion criteria,according to the random number table,random numbers are drawn and divided into 2 groups,35 cases in each group.The control group was treated with oral celecoxib,once a day;the treatment group was treated with row warm acupuncture on the basis of the control group.Acupuncture and warm needling were treated 5 times a week;both treatment and control groups were treated for 4 weeks.Detailed records of the general information of the two groups of patients,overall evaluation of the patient’s own disease(PGA),spinal pain,Bath Ankylosing Spondylitis Disease Activity Index(BASDAI),Bath Ankylosing Spondylitis Disease Function Index(BASFI),C-reactive protein 、 ESR and TCM syndrome scores before and after treatment Grading quantitative scoring index,ASAS20 efficacy evaluation after treatment.Use Windows SPSS 23.0statistical software for data statistics,analyze and compare the efficacy of the two groups.Results:1.Before treatment,there was no significant difference in general data,BASDAI score,BASFI score,laboratory index(ESR,CRP)level and TCM symptom score between the two groups(P>0.05),which were comparable.2.PGA and spinal pain scores: After 4 weeks of treatment,the PGA and spinal pain scores of both groups were lower than before(P<0.05),and the treatment group was lower than the control group(P<0.05).3.BASDAI score: After 4 weeks of treatment,the BASDAI scores of the two groups of patients were lower than before(P<0.05),and the treatment group was lower than the control group(P<0.05).4.BASFI score: After 4 weeks of treatment,the BASFI scores of both groups were lower than before(P<0.05),and the treatment group was significantly lower than the control group(P<0.05).5.Laboratory indicators(ESR,CRP): After 4 weeks of treatment,the laboratory indicators(ESR,CRP)of the two groups of patients were lower than before(P<0.05),and the treatment group was significantly lower than the control group(P<0.05).6.Grading and quantitative scores of TCM syndrome scores:After four weeks of treatment,the total TCM syndrome score of the two groups of patients was lower than before treatment(P<0.05),and the treatment group was lower than the control group(P<0.05).7.ASAS20 efficacy statistical analysis: After 4 weeks of treatment,the effective rate of the treatment group was 77.14%;while the control group was 52.94%.The effective rate of the treatment group was higher than that of the control group(P<0.05),and the difference was statistically significant.Conclusions:1.Row warm acupuncture combined with celecoxib and celecoxib alone are effective in treating ankylosing spondylitis of kidney deficiency and du-meridian cold syndrome.2.The combination of row warm acupuncture with celecoxib is more prominent than celecoxib alone in reducing pain and disease activity,improving patients’ daily living ability,reducing inflammation level,and improving TCM symptoms,and has fewer adverse reactions and good safety.