Analysis Of Extrapulmonary Complications Of Mycoplasma Pneumoniae Pneumonia In Children

Objective : To explore the epidemiology,clinical manifestations and laboratory characteristics of extrapulmonary complications of Mycoplasma pneumoniae pneumonia(MPP)in children,as well as the risk factors of myocardial damage and central nervous system damage caused by Mycoplasma pneumoniae(MP),so as to improve clinicians’ understanding of the extrapulmonary complications of MPP,and achieve early diagnosis and treatment.Methods:Children with MPP who were hospitalized in our hospital from November 1,2015 to July 31,2019 were selected as the study subjects,and their medical records were collected.According to the presence or absence of extrapulmonary complications,they were divided into two groups: MPP without extrapulmonary complications group and MPP extrapulmonary complications group.Descriptive statistics and univariate analysis were used for the epidemiology,clinical manifestations and laboratory characteristics of MPP extrapulmonary complications.Univariate analysis and multivariate Logistic regression analysis were used for the risk factors of mycoplasma pneumoniae myocardial damage and central nervous system damage.Results: There were no statistical differences in average age,gender,delivery mode and feeding mode between the two groups(P > 0.05),and there were statistical differences in hospital weight.There were no significant differences in gender,mean age,delivery mode,admission weight and feeding mode between MPP combined with myocardial damage group and MPP combined with central nervous system damage group(P > 0.05).The incidence of extrapulmonary complications of MPP was different in different age groups,and the infant group was lower than the elderly group,the difference was statistically significant(P<0.05).MPP with myocardial injury group and simple in the WBC,CRP,CKMB with significant difference(P < 0.05),and heating time,high fever,MP(1:16 0 or higher)antibody concentration,poor spirit had no significant difference(P > 0.05),the MPP merger of the central nervous system damage and pure group in CRP,high degree of MP antibody(1:16 0 or higher),degree of fever with significant difference(P < 0.05),while the WBC,heating time,breath sounds crude there was no significant difference(P > 0.05).There were significant differences in fever degree,WBC and CRP between the simple group and the combined group(P<0.05),but no significant differences in fever time and high MP antibody titer(≥1:160)(P >0.05).Conclusions: 1.The incidence of extrapulmonary complications of MPP was different in different age groups,and the infant group was lower than the elderly group.2.High WBC and CRP are independent risk factors for MPP complicated with myocardial damage.3.High CRP was an independent risk factor for MPP combined with central nervous system damage,and high MP titer was a protective factor.This provides theoretical support for the prevention,detection and clinical treatment of extrapulmonary complications of Mycoplasma pneumoniae pneumonia in children,facilitating early detection and timely treatment of the disease and improving the quality of life of patients.