Clinical Observation On Treatment Of Primary Dysmenorrhea Of Cold Congealing And Blood Stasis Type By Acupuncture Combined Acupoint Application

Objective:To evaluate the clinical efficacy of acupuncture in combination with acupoint paste on patients with primary dysmenorrhea caused by cold clotting and blood stasis before and after the treatment,the changes of indexes and improvement of symptoms were observed.Methods:The 72 patients who met the inclusion criteria were randomly grouped into treatment group and control group,36 patients in each group.The treatment group was treated with acupuncture and acupuncture point paste from 7 days before menstruation to the onset of menstruation,once a day for7 days.In the control group,oral ibuprofen extended-release capsules were selected and started 1 day before menstruation for 3 days.Both groups were treated for 3 menstrual cycles and followed up once in 3 months after the end of treatment.To observe the changes of VAS score,dysmenorrhea symptom score and serum estradiol before treatment and after three menstrual cycles in the treatment group and the control group,and to record the dysmenorrhea symptom score and VAS score after three months of treatment,and to observe the clinical efficacy of acupuncture and "warming the uterus patch" in treating primary dysmenorrhea with cold clotting and blood stasis.The clinical efficacy of acupuncture combined with "warming the uterus patch" in treating primary dysmenorrhea with cold clotting and blood stasis was observed.Result:1.72 patients were included in this study,and a total of 67 cases completed clinical observation and were included in the statistics.2 cases were shed in the treatment group and 3cases were shed in the control group,with an overall shed rate of 6.9%.2.The differences in age,age at menarche and duration of disease between the two groups before treatment were not statistically significant(P>0.05),and the differences in VAS score,dysmenorrhea symptom score between the two groups before treatment were not statistically significant(P>0.05)and were comparable.3.VAS score、dysmenorrhea symptom score:after treatment,the dysmenorrhea symptom scores and VAS scores decreased in both groups compared with those before,and the difference between the two groups was not statistically significant(P>0.05),indicating that there was no significant difference in the improvement of dysmenorrhea symptom scores and VAS scores between the two groups recently.In the follow-up treatment group,the improvement of dysmenorrhea symptom scores and VAS scores was better than that of the control group,and the difference was statistically significant(P<0.05).4.Comparison of serum estradiol levels:After treatment,serum estradiol levels in the treatment group decreased significantly compared with those before treatment,and the difference was statistically significant(P<0.05),while serum estradiol in the control group did not show a significant decrease,and the difference was not statistically significant(P>0.05).5.Comparison of clinical efficacy: The recent total effective rate of the treatment group was 94.12%,and the recent total effective rate of the control group was 84.84%,and the difference was not statistically significant(P>0.05),indicating that the recent efficacy of the two was similar.At follow-up,the total long-term effective rate was 88.24% in the treatment group and 48.48% in the control group(P<0.05),and the difference was statistically significant,indicating that the long-term efficacy of the treatment group was better than that of the control group.6.Clinical safety analysis: Under the existing test conditions,patients in the treatment and control groups did not show any abnormalities in the safety indicators monitored during this study,and no adverse reactions related to this study were observed.Conclusion:1.The clinical trial showed that both treatment protocols were effective in improving the pain symptoms and degree of the patients,and the recent efficacy was similar,but the long-term efficacy of the acupuncture with "warming the uterus patch" group was better than that of the control group and was more durable and stable.2.Acupuncture combined with "warming the uterus" acupuncture point application could reduce the serum estradiol level of patients,and it was better than the control group.