Based On Data Mining To Explore The Medication Rules Of Chinese Medical Masters In The Treatment Of Chest Stuffiness And Heartache

Objective:To explore the medication rules of traditional Chinese medicine masters in the treatment of chest stuffiness and heartache,so as to provide reference for clinical treatment,inheritance of the medication experience of traditional Chinese medicine masters and drug research and development.Methods:To screen the prescriptions in the classic works and journal articles of the masters of traditional Chinese medicine,establish a database,and use the method of data mining to analyze the medication rules of the prescriptions for the treatment of chest stuffiness and heartache,including the analysis of four Qi and five flavors,the statistics of commonly used drugs,the statistics of commonly used drugs,the consumption analysis of commonly used drugs,the mining of commonly used drug pairs,the compatibility research of commonly used drug pairs,and the mining of new prescriptions noodles.1.The four Qi properties of the drugs used by the masters of traditional Chinese medicine in the treatment of chest stuffiness and heartache are both cold and warm,but most of them are warm drugs;most of the five flavors are sweet,bitter and pungent;most of them belong to the heart,liver and spleen meridians.2.The top 10 commonly used drugs for treating chest stuffiness and heartache are Salvia miltiorrhiza,Poria cocos,Codonopsis pilosula,Ligusticum chuanxiong,Trichosanthes kirilowii,Pinellia ternata,Ophiopogon japonicus,Astragalus membranaceus,Angelica sinensis and Schisandra chinensis.3.The common drugs used by the masters of traditional Chinese medicine to treat chest stuffiness and heartache are tonifying drugs,promoting blood circulation and removing blood stasis drugs,promoting Qi drugs and resolving phlegm drugs.4.When the masters of traditional Chinese medicine treat chest stuffiness and heartache,the minimum dose of Salvia miltiorrhiza,Codonopsis pilosula,Trichosanthes kirilowii and Astragalus membranaceus is 9g,the minimum dose of Poria cocos and Ophiopogon japonicus is 6g,the minimum dose of Ligusticum chuanxiong and Schisandra chinensis is 3g,and the minimum dose of Pinellia ternata and Angelica sinensis is 5g;The highest dose of Salvia miltiorrhiza,Poria cocos,Trichosanthes kirilowii and Angelica sinensis is 50 g,the highest dose of Codonopsis pilosula,Ligusticum chuanxiong and Schisandra chinensis is 30 g,the highest dose of Pinellia ternata is 20 g,the highest dose of Ophiopogon japonicus is 80 g and the highest dose of Astragalus membranaceus is 100g;Results:The most commonly used dose of Salvia miltiorrhiza,Poria cocos,Codonopsis pilosula,Trichosanthes kirilowii and Angelica sinensis is 15 g,the most commonly used dose of Ligusticum chuanxiong,Pinellia ternata and Schisandra chinensis is 10 g,the most commonly used dose of Ophiopogon japonicus is 12 g,and the most commonly used dose of Astragalus membranaceus is 20 g.5.The top 20 common drug pairs used by Chinese medical masters to treat chest stuffiness and heartache are“Ligusticum chuanxiong-Salvia miltiorrhiza”,“Salvia miltiorrhiza-Codonopsis pilosula”,“Ophiopogon japonicus-Salvia miltiorrhiza”,“Salvia miltiorrhiza-Trichosanthes kirilowii”,“Ophiopogon japonicus-Schisandra chinensis”,“Salvia miltiorrhiza-Astragalus membranaceus”,“Allium macrostemon-Trichosanthes kirilowii”,“Salvia miltiorrhiza-Poria cocos”,“Salvia miltiorrhiza-Schisandra chinensis”,“Salvia miltiorrhiza-Angelica sinensis”,“Pinellia ternata-Poria cocos”,“Pinellia ternata-Salvia miltiorrhiza”,“ Radix Paeoniae Rubra-Salvia miltiorrhiza ”,“ Allium macrostemon-Salvia miltiorrhiza”,“Ligusticum chuanxiong-Astragalus membranaceus”,“Pinellia ternata-Trichosanthes kirilowii”,“Codonopsis pilosula-Poria cocos”,“Codonopsis pilosula-Angelica sinensis ”,“ Codonopsis pilosula-Astragalus membranaceus”,“Salvia miltiorrhiza-Fructus aurantii”.6.The compatibility of common drug pairs in the treatment of chest stuffiness and heartache by traditional Chinese medicine masters is mostly the mutual compatibility of high-frequency drugs.For example,"Ligusticum chuanxiong-Salvia miltiorrhiza" pair is often used in combination with Astragalus membranaceus,Ophiopogon japonicus,Schisandra chinensis and radix paeoniae rubra,and "Ligusticum chuanxiong-Astragalus membranaceus" pair is often used in combination with Salvia miltiorrhiza,Angelica sinensis,Schisandra chinensis,Ophiopogon japonicus and Codonopsis pilosula,etc.7.Four new prescriptions are excavated,namely: new prescription 1: Zhuru,tangerine,Pinellia ternata,Codonopsis pilosula,Allium macrostemon,Trichosanthes kirilowii;new prescription 2: Zhuru,tangerine,Poria cocos,Poria cum Ligno Hospite,Polygala tenuifolia,Acorus tatarinowii;new prescription 3: Zhuru,Ligusticum Chuanxiong,Poria cocos,Fructus aurantii,tangerine,Humulus scandens;new prescription4: Pollen Typhae,Pinus tabulaeformis,Wulingzhi,Nine fragrant insects,Honey ephedra.Conclusion:1.Traditional Chinese medicine masters treat chest stuffiness and heartache from "deficiency","blood stasis","Qi" and "phlegm".The specific treatment methods include warming and tonifying yang qi,reducing heat,promoting Qi,activating blood circulation,resolving phlegm,nourishing yin and so on.Especially pay attention to tonifying deficiency,promoting blood circulation,promoting qi and resolving phlegm.2.Traditional Chinese medicine masters use sweet,bitter and pungent drugs to treat chest stuffiness and heartache.3.Traditional Chinese medicine masters mostly treat chest stuffiness and heartache from liver,spleen and heart.It is suggested that liver Qi is the main source of relieving and discharging,spleen and stomach are the main source of ascending and descending turbidity,and heart is the main source of blood vessels.4.In the treatment of chest stuffiness and heartache,the masters of traditional Chinese medicine often combine the classic Tongyang pair of classical prescriptions with the Tongyang pair of seasonal prescriptions,combine the characteristics of modern clinical pathogenesis,and make prescriptions based on syndrome differentiation and subtraction,which reflects that the masters of traditional Chinese medicine are good at integrating new knowledge,combining the clinical characteristics of the times,flexible and flexible,learning from the past rather than the past on the basis of inheriting the experience of the ancients.