Research On The Correlation Between Cardiac Function And Ankle/Brachial Index And TCM Syndromes In Patients With Arteriosclerosis Obliterans Of Lower Extremities

Objective:Under the guidance of the theory of "heart dominating blood and vessels",to explore the distribution rule of Cardiac function and ankle/brachial index(ABI)in different TCM Syndromes of patients with arteriosclerosis obliterans of lower extremity,and to further improve the TCM syndrome differentiation and classification standard.It also provides a modern scientific basis for the theory of "heart dominates blood vessels".Methods:80 patients with arteriosclerosis obliterans of lower extremities were selected as the observation group,including 40 cases of blood stasis syndrome,40 cases of deficiency of Qi and blood,and 20 cases of normal control group.The systolic blood pressure,diastolic blood pressure,pulse pressure,total cholesterol,triglyceride,high-density lipoprotein(HDL),low-density lipoprotein,ABI,left ventricular ejection fraction(LVEF),N-terminal pro brain natriuretic peptide(NT-proBNP),New York Heart Association(NYHA)cardiac function grading level were collected and sorted out,and the observation indexes were statistically analyzed.Results:The observation group systolic blood pressure,pulse pressure difference,total cholesterol,NT-proBNP compared with the control group significantly increased,HDL,ABI,LVEF compared with the control group significantly decreased,the observation group NYHA cardiac function grading level and control group has a significant difference.deficiency of Qi and blood syndrome group HDL,LVEF than blood stasis syndrome group decreased,NT-proBNP than blood stasis syndrome group increased.In the observation group,LVEF was negatively correlated with NT-proBNP and NYHA cardiac function grading,while NT-proBNP was positively correlated with NYHA cardiac function grading.In the observation group,ABI<0.4 group and 0.4≤ABI≤0.7 group,ABI>0.7 group,LVEF significantly decreased,NT-proBNP significantly increased,NYHA cardiac function classification differences.There was no significant difference in LVEF,NT-proBNP and NYHA cardiac function grading between ABI>0.7 group and 0.4≤ABI≤0.7 group.Conclusion:There are differences between HDL,LVEF and NT-proBNP in lower extremity arteriosclerosis obliterans syndrome of Qi and blood deficiency and blood stasis syndrome,and there is a certain correlation between lower extremity arteriosclerosis obliterans patients’ cardiac function level and ABI.The cardiac function of the patients with ABI<0.4 was significantly lower than that of the patients with 0.4≤ABI≤0.7 and ABI>0.7.There was no significant difference in cardiac function between 0.4≤ABI≤0.7 group and ABI>0.7 group.