Clinical Study Of Wujisan In The Treatment Of Non-alcoholic Steatohepatitis With Internal Resistance Of Phlegm And Dampness

ObjectiveTo observe the changes of body weight coefficient,liver biochemical index,inflammatory factor and liver controlled attenuation parameters in patients with non-alcoholic fatty hepatitis with phlegm and dampness induced by Wuji powder by more systematic clinical research.Thus,objective and systematic evaluation of the effect of Wujiasong on sputum dampness type NASH,provide a new method for the treatment of NASH,and through this study to master the basic methods of clinical research.MethodsAccording to the theory of traditional Chinese medicine,66 patients with non-alcoholic fatty hepatitis with phlegm and dampness resistance were selected according to the modern medical auxiliary test method.The experimental group/control group/experimental group/control group/control group/control group/control group/control group were selected according to the order of treatment.In each of the 33 cases,the experimental group gave Wujiasan one morning and five times a week an aerobic exercise/control of sugar fat intake of 30 minutes and 1 iver protection treatment of Shuifi thrips.The control group gave 5 times a week.30 minutes of aerobic exercise,control of sugar fat intake,and liver protection treatment of Shuifu thrips.The two groups were treated for 3 months,and the improvement of relative indexes before,after and between the two groups was observed.ResultsThere were no significant differences in gender,age,BMI and other general data between the experimental group and the control group(P>0.05).The baseline between the two groups was balanced and comparable.The body weight,BMI,TCM syndrome points,CAP,ALT,GGT,UA,TG,TNF-? were significantly decreased in the experimental group and control group before and after treatment,and there were differences(P<0.05),which were statistically significant.The total efficiency of the experimental group was higher than that of the control group,and there were differences(P<UNK>0.0,5),which was statistically significant.The decrease of CAP and TCM syndromes in the experimental group before and after treatment was more obvious than in the control group.ConclusionWuji powder can effectively improve the reduction of body weight in patients with non-alcoholic fatty hepatitis with dampness,improve symptoms such as body weight,fatigue,abdominal distension,and improve CAP,liver function,TG,UA and other indicators.The safety is good and there is no obvious adverse reaction,and it is worth clinical promotion.Its mechanism may reduce the oxidative stress of liver cells and relieve insulin resistance.