Clinical Observation On The Treatment Of Non-alcoholic Steatohepatitis Of Phlegm And Blood Stasis With The Method Of Regulating Mechanism And Removing Stagnation

Purpose:To observe the clinical efficacy and safety of tiaojihuazhi in the treatment of phlegm and blood stasis mixed non-alcoholic steatohepatitis,and to provide some references for the treatment of non-alcoholic steatohepatitis with traditional Chinese medicine.Material and method:119 patients meeting the inclusion criteria were selected and randomly divided into control group and observation group.There were 59 patients in the control group who took qiangan capsule orally.There were 60 patients in the observation group who took orally the decoction(10g tangerine peel,10 g abdominal peel,15 g magnolia officinalis,15 g atractylodes atractylodes,10 g hawthorn,6g red koji,10 g alisma,5g rhubarb).Other basic treatments are the same(patients are advised to keep regular work and rest,adjust diet structure,reasonable exercise,etc.).By observing two groups of patients before and after12 weeks of treatment on the improvement of their clinical symptoms and serum biochemical indexes,liver function(ALT,AST,GGT)and blood lipids(TC,TG,HDL-C,LDL-C)and the degree of liver colour to exceed,statistical analysis,the comprehensive assessment of tuning machine delay method liquid form of phlegm and blood stasis mutual junction in patients with nonalcoholic fatty hepatitis treatment effect,at the same time observe patients electrocardiogram,blood in urine routine,renal function,etc.As a safety measure.Results:There was no significant difference in gender,age,course of disease and other basic conditions between the two groups(P>0.05),which was comparable.The clinical symptoms and signs,as well as the liver function,blood lipid and other physical and chemical indicators and liver color doppler ultrasound grading of the two groups of patients were improved or decreased in different degrees compared with before treatment,and the differences were statistically significant(P < 0.05).The improvement of TCM syndromes in the observation group was greater than that in the control group after treatment,and the difference was statistically significant(P < 0.05).The decreased levels of ALT,AST,GGT,TC,TG and ldl-c in liver function of the observation group were better than those of the control group,and the differences were statistically significant(P < 0.05).The grading degree of the two groups of drugs on patients' liver color doppler ultrasound was similar,and thedifference was not statistically significant(P>0.05).Conclusion:The method of tiaojihuazhi can reduce the liver function,blood lipid and other laboratory indexes in patients with non-alcoholic steatohepatitis with mixed phlegm and blood stasis,reduce liver inflammatory reaction,improve liver fat infiltration,and relieve clinical symptoms.Moreover,the comprehensive effect is better than qiangan capsule,which is worthy of further promotion and application in clinical practice.