A Retrospective Study Of The Factors Affecting The Degree Of Tics In 575 Children With TD

Objective:To investigate the related factors affecting the degree of twitching in children with TD,and to provide a reliable clinical basis for the treatment and adjustment of children with TD.Methods:From January 2013 to October 2018,575 TD scientific research medical records of the Oriental Hospital of Beijing University of Chinese Medicine were selected.According to the YGTSS score,they were divided into mild group(242 cases)and moderately severe group(333 cases)according to the degree of twitching.General conditions,birth history and sensory integration,past history,family history,personal habits,mental emotional stimulation,comorbidities,Western diagnostic classification,TCM syndrome classification and other information.The data was statistically analyzed using EXCEL and SPSS20.0 software.Result:1.General:Of the 575 children enrolled in the study,456 were male and 119 were female,with a male to female ratio of 3.83:1.The average age of onset was(6.33±2.13)years.It is the most common onset in spring and summer,accounting for 63.8%of the year.Analysis results:gender,onset age,onset season and twitching degree were not correlated(P>0.05).2.Personality characteristics:42%of those with timidity and 70.3%of those with irritability,and the two were not related to the degree of twitching in children with TD(P<0.05).3.Past history and allergic history:9.9%of those with previous history of seizures and 10.6%with history of allergies,and the two were not related to the degree of twitching in children with TD(P>0.05).4.Birth history:250 children(43.47%)with cesarean section,325 cases(61.23%)with cesarean section;42 cases(7.3%)with premature delivery,533 cases(92.7%)with full-term birth,and twitching degree with TD children Relevant(P>0.05).5.Sensory integration:238 cases(41.4%)who ate the rice grains,and 59 cases(10.26%)were not climbed.The two were not related to the twitching degree of TD children(P>0.05).6.Personal eating habits:155 cases(26.96%)who regularly consumed carbonated drinks,and 18 cases(3.13%)who often consumed caffeinated foods,which were not related to the degree of twitching in children with TD(P>0.05);213 cases(37.04%)who regularly ate foods containing food additives,which was not related to the degree of twitching in children with TD(P>0.05).7.Usage of electronic products:282 cases(49.04%)of electronic products were frequently used for a long time,which was related to the degree of twitching in children with TD(P<0.05).8.Emotional stimulation:243 children(42.26%)had emotional stimuli,which was related to the degree of twitching in children with TD(P<0.05).9.comorbidities:333 patients(57.9%)had comorbidities,of which 233 patients(40.5%)were the most common,and 138(24%)patients with streptococcal infections shared recurrent respiratory tract.58 patients(10.1%)were infected.In addition,children with TD were also associated with other comorbidities,including enuresis,obsessive-compulsive disorder,mood disorder,asthma,eczema,and allergic rhinitis.Some children had multiple comorbidities.The presence of comorbidities was associated with twitching in children with TD(P<0.05).10.Western medicine diagnosis classification:383 cases(66.6%)diagnosed as TS in Western medicine,112 cases(19.5%)in TTD,and 80cases(13.9%)in CTD were not associated with twitching degree in children with TD(P>0.05).11.TCM syndrome classification:spleen deficiency and liver stagnation syndrome are the most common,353 cases(61.4%),followed by liver phlegm and blood stasis syndrome in 87 cases(15.1%),spleen deficiency syndrome(40 cases(7%),bonfire 34 cases(5.9%)were disturbed by the syndrome,29 cases(5%)were external stimuli,25 cases(4.3%)were qi-deficiency syndrome,and only 7 cases(1.2%)were qi-stagnation syndrome.According to statistics,the TCM syndrome classification of children with TD was not correlated with the degree of tics(P>0.05).12.Univariate analysis found that the factors related to the severity of TD children were:irritable personality,regular consumption of foods containing more additives,prolonged use of electronic products,streptococcal infection,emotional stimulation,comorbidity,on these 6 The factors were analyzed by ordered multi-class logistic regression.The statistically significant results were streptococcal infection,emotional stimulation and comorbidity.Conclusion:1.TD occurs in spring and summer,the ratio of male to female is 3.83:1,and the average age of onset is(6.33±2.13)years old..2.Factors that are significantly associated with the severity of twitching in children with TD are streptococcal infections,emotional stimuli,and comorbidities.3.TS is most common in the diagnosis of Western medicine in children with TD;the syndrome of TCM syndrome is the most common in the syndrome of spleen deficiency and liver stagnation,followed by the syndrome of liver stagnation and qi stagnation.4.ADHD is the most common in children with TD,and affects the degree of tics in children.