Clinical Observation On The Treatment Of Acute Radiation Enteritis With Shenlingbaizhu Powder Combined With Oral Administration And Retention Enema

Objective: To observe the clinical curative effect,adverse reaction and safety of traditional Chinese medicine shenling baishu combined with oral administration of enema in the treatment of acute radiation enteritis.Methods: According to the randomized control principle,Removal of exfoliation,removal of cases and cessation of treatment.Will be included in the standard of 60 cases were divided into two groups,treatment group 30 cases,three atractylodes scattered flavored oral with retention enema therapy)and control group 30 cases(montmorillonite powder oral joint 0.9% sodium chloride50ml+montmorillonite powder 9g +dexamethasone 5mg retention enema).Two groups of patients treatment for 2 weeks,stop using other drugs during treatment,two groups of adverse reaction in the process of treatment cure all use the same method,compare the symptoms integral,colonoscopy under change,the quality of life(KPS score),adverse reaction and safety indicators,such as observing two groups of clinical curative effect.Using the statistical software SPSS19.0 data statistical analysis.Result:1.Compared with the two groups of symptoms,the symptoms of posttreatment syndrome were improved in different degrees(P<0.05).Among them,the defecation,abdominal pain,hematopoiesis,and acute and postsecondary symptoms of the treatment group were significantly improved compared with the control group,and the difference was statistically significant(P<0.01).2.Compared with the mucosal injury in the colonoscopy,after treatment,the mucosal injury was less than that before treatment.After treatment,the number of patients in the treatment group was better than that of the control group after treatment,and the difference was statistically significant(P<0.05),indicating that the combination of oral and oral combined enema could effectively promote the recovery of intestinal mucosal injury.3.Comparing the quality of life in the two groups,the KPS scores of both groups wereincreased after treatment,and the difference was statistically significant(P=0.015<0.05).After treatment,KPS increased significantly,indicating that it had obvious advantages in improving KPS score.4.The clinical efficacy was analyzed,the effective rate of the treatment group was96.66%,and the effective rate of the control group was 93.33%.The difference between the two groups was statistically significant(P=0.037<0.05),and the efficacy of the treatment group was better than that of the control group.5.Comparison of safety and adverse reactions: there was no statistically significant difference between the two groups,no obvious adverse reactions and side effects.Conclusion: The treatment group is better than the control group in the syndrome of Chinese medicine,and the quality of life and the clinical efficacy of the treatment group,which means that it is a good idea to treat the clinical efficacy of the enema with the oral association of the enema,which is superior to the simple western medicine.