Clinical Observation Of Compound Huangkui Granules In The Treatment Of Chronic Nonbacterial Prostatitis Of Damp-Heat Stasis Type

Objective In this study,observation of oral compound Huangkui granules on chronic prostatitis symptom scores(NIH-CPSI),TCM syndrome scores,white blood cell counts and lecithin bodies in routine examination of prostatic fluid in patients with chronic nonbacterial prostatitis with damp heat syndrome The objective is to objectively evaluate the clinical efficacy of Compound Huangkui Granule in the treatment of chronic nonbacterial prostatitis with damp heat syndrome.Methods Choose to go to the urology clinic of the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine from December 2017 to December 2019,aged between 18-55 years old,refer to Western medicine about type ?A prostatitis and Chinese medicine about dampness-heat stasis type chronic prostatitis.According to the enrollment criteria established,52 patients who met the inclusion and exclusion criteria were screened out and randomly divided into two groups: test group(39 cases)and control group(13 cases).The test group was given oral standard Compound Huangkui granules,and the control group was given oral simulated Compound Huangkui granules.Both groups were followed by outpatient or telephone follow-up before treatment,at the 4th and 8th week after treatment,and recorded the chronic prostatitis symptom index(NIH-CPSI)scores,TCM symptom scores,and prostatic fluid before and after treatment in the test and control groups,Routine tests such as white blood cell count,lecithin body number and other related sub-indicators and adverse reactions were analyzed and analyzed using statistical methods.Results (1)In the experimental group,0 cases(0.00%)were cured,23 cases(63.89%)were markedly effective,8 cases(22.22%)were effective,5 cases(13.89%)were ineffective,and the total effective rate was 86.11%.In the control group,0 cases(0.00%)were cured,3 cases were markedly effective(25.00%),1 case was effective(8.33%),8 cases were ineffective(66.67%),and the total effective rate was 33.33%.There was a significant difference ineffective rate between the two groups after treatment(P<0.01).(2)After treatment,the total CPSI score,pain discomfort score,urination symptom score,and quality of life score of the two groups were significantly lower than those before treatment(P<0.05);the control group at 8 weeks after treatment and at 4 after treatment There was no significant difference between the weeks(P>0.05).Comparison between groups: At 8weeks after treatment,the test group had a lower NIH-CPSI score than the control group,and the difference was significant(P<0.05);the test group had a lower pain discomfort score than the control group,the difference was significant(P<0.01).(3)In the 4th and 8th weeks after treatment,the TCM symptom scores of the two groups were lower than before treatment,and the difference was significant(P<0.05);the 8th week after treatment in the experimental group was higher than the 4th week after treatment.The symptom score was significantly reduced,and the difference was significant(P<0.01);there was no significant difference between the groups(P>0.05).(4)Compared with before treatment,the EPS white blood cell count decreased in the 4th week after treatment and the 8th week after treatment in both groups,the difference was significant(P<0.05);At week,the white blood cell count decreased significantly and the difference was significant(P<0.01);there was no significant difference between the groups(P>0.05).In the experimental group,the lecithin body counts increased at 4 weeks after treatment and at 8 weeks after treatment,and the differences were significant(P <0.05);the control group at 8 weeks after treatment was better than at 4 weeks after treatment.The lecithin body count increased before treatment,and the differences were significant(P <0.05);there was no significant difference between the groups(P> 0.05).Conclusion(1)Compound Huangkui Granules can effectively improve the NIH-CPSI score and TCM symptom scores of patients with damp-heat stasis-type CNP,especially for patients with prostate area pain symptoms and quality of life.(2)Compound Huangkui Granules can objectively reduce the normal white blood cell count of prostate fluid and increase the number of lecithin bodies.