Clinical Observation On The Treatment Of Chronic Nonbacterial Prostatitis With Dampness-heat Stasis By Promoting Lung And Clearing Heat And Activating Blood Circulation

Purposes:This study aims to compare the efficacy and safety of Xuanfei-clearing heat-promoting blood circulation and Tamsulosin,the recommended clinical treatment plan,in chronic nonbacterial prostatitis of dampness-heat stasis type,in order to provide new ideas and theoretical basis for clinical treatment of chronic nonbacterial prostatitis of dampness-heat stasis type.Methods:In this study,patients with chronic nonbacterial prostatitis(CNP)with dampness-heat stasis syndrome who visited the urological outpatient department of Kunming Yan ’an Hospital and Yunnan Hospital of Traditional Chinese Medicine from November 2021 to December 2022 were enrolled by comparing the treatment of Xuanfei-clearing heat and promoting blood circulation and the recommended clinical treatment plan--Tamsulosin.According to the principle of randomized control,they were divided into treatment group and control group(n=36,36).The treatment group was treated with Xuanfei,clearing heat and promoting blood circulation,and the control group was treated with Tamsulosin.The treatment course was 4 weeks.Before and after treatment,the symptoms of patients were scored by traditional Chinese Medicine syndrome scale,Chronic Prostatitis Symptom Index(NIH-CPSI)and prostate specialized examination scale,and the case data were collected.The therapeutic effects of the two treatment schemes were evaluated and compared by statistical methods.Results:1.2 There was no statistical difference in the general information(age and course of disease)of the patients in the groups before treatment,which was comparable.2.After 4 weeks of treatment,the total clinical effective rate of the treatment group was better than that of the control group(83.87%vs.67.74%,P<0.01),and the effective rate of the treatment group in TCM syndrome was 87.10% and that of the control group was 74.19%(P<0.01),indicating that the clinical effect of the treatment group was better than that of the control group.3.After 4 weeks of treatment,the improvement of TCM syndrome score,NIH-CPSI score and white blood cell score in prostatic fluid routine in 2 groups was better than before treatment(P<0.05),indicating that the drugs used in the treatment group and the control group were effective.4.From the perspective of the total scores of TCM syndromes,the scores of patients in both groups after treatment were better than those before treatment(P<0.05).The treatment group was better than the control group in the improvement of urgent urination,incomplete urination,odynuria,burning urination,dry mouth,bitter mouth,wet scrotum,perineum or anus,less abdominal pain or discomfort(P<0.05),but there was no difference between the two groups in the improvement of symptoms of urinary frequency,lumbosacral pain or discomfort(P>0.05).Conclusions:1.The method of Xuan lung,clearing heat and activating blood circulation can significantly improve the symptoms of urgent urination,incessant urination,painful urination,burning urination,dry mouth and bitter mouth,damp scrotum,perineum or anus,and less abdominal pain or discomfort in patients with CNP of damp-heat and stasis type.2.The clinical effect of Xuan lung,clearing heat and activating blood in the treatment of CNP with damp-heat stasis is better than that of tamsulosin alone.