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Observation Of Tu Fuling Shi Du Granule In Treating Recurrent Genital Herpes

Posted on:2021-02-16Degree:MasterType:Thesis
Country:ChinaCandidate:M YanFull Text:PDF
GTID:2404330611980164Subject:Chinese traditional surgery
Abstract/Summary:PDF Full Text Request
Objective:To observe the clinical effect of Tufulingshidu granules in recurrent genital herpes(syndrome of lingering pathogen due to vital qi deficiency).Methods:From the Department of Dermatology,the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,72 patients with recurrent genital herpes(syndrome of lingering pathogen due to vital qi deficiency)that met the inclusion criteria were selected.The patients were randomly divided into a treatment group and a control group.The treatment group:A total of 36 patients were treated with oral tufulingshidu granules combined with topical acyclovir cream;control group:a total of 36 patients were treated with oral famciclovir capsules combined with topical acyclovir cream.The two groups of patients were treated before and after treatment with the second At the end of each month,the fourth month,and the sixth month,the medication response of the patients during the treatment period was recorded,and the HAMD questionnaire score changes in the frequency of recurrence during the treatment observation period to evaluate the effectiveness and safety of the drugResults:72 patients in this study met the incl.usion criteria.During the process,a total of five patients fell off(2 in the treatment group and 3 in the control group).The total fall-off ratio was 6.9%,less than 10%.The number of completed cases was 67(34 in the treatment group),33 cases in the control group).After treatment in this clinical study,10 cases were cured in the treatment group,17 cases were clinically improved.The total effective rate was 79.4%,which was higher than 42.4%in the control group.The total effective rate in the treatment group was significantly better than that in the control group(P<0.05),with significant differences.The recurrence frequency and HAMD score of the two groups were improved before and after treatment,but the improvement degree of the treatment group was significantly better than that of the control group(P<0.05),with a significant statistical difference.Adverse reactions:During treatment,diarrhea,abdominal pain,nausea,and insomnia appeared in both groups and/or.After carefully inquiring the patient's medication situation and taking clinical intervention measures,the patient's adverse symptoms reduced or disappeared.The above adverse reactions were not related to the drug composition and dose,and did not affect the clinical study.Conclusions:1.Tufulingshidu granules combined with topical acyclovir cream can effectively improve the frequency of recurrence in patients with recurrent genital herpes(syndrome of lingering pathogen due to vital qi deficiency),and the effect is better than oral famciclovir capsules combined with topical acyclovir cream,which is more stable and lasting.2.Tufulingshidu granules combined with topical acyclovir cream for the treatment of recurrent genital herpes(syndrome of lingering pathogen due to vital qi deficiency)are safe and effective.
Keywords/Search Tags:Recurrent genital herpes, Tufulingshidu granules, Depression, Clinical observation
PDF Full Text Request
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