Clinical Observation Of Xiangbikang In Treating Cervical Spondylotic Radiculopathy(Wind-cold Obstruction Type)and Its Influence On Hemorheology

Objective:The purpose of this study was to evaluate the clinical efficacy of Xiangbikang in treating cervical spondylotic radiculopathy(wind cold and obstruction type),and to evaluate the improvement of Xiangbikang's symptoms on patients with this disease and its effect on hemorheological indexes,and further verify the scientificity and rationality of Xiangbikang in the treatment of cervical spondylotic radiculopathy.Methods:90 patients with cervical spondylotic radiculopathy treated in the Department of Orthopaedics of Yangzhou Traditional Chinese Medicine Hospital from February 2018 to February 2020,were randomly divided into observation group,control group 1 and control group 2 according to the method of random number table,Each group had 30 cases.The observation group was given Xiangbikang orally,the control group 1 was given Jingtong granules,the control group 2 was given celecoxib on the basis of the treatment of control group 1.One week was a course of treatment,two courses of treatment were observed continuously.The VAS score,score of symptoms and signs,SF-36 score,hemorheology parameters of the three groups were observed before treatment,the first week and the second week after treatment to evaluate the clinical efficacy and changes in hemorheology parameters.Results:(1)There was no significant difference in VAS scores among the three groups of patients before treatment(P>0.05).The VAS scores in the first and second weeks after treatment were lower than those before treatment(P<0.05).The VAS scores of the observation group and the control group 2 in the second week after treatment were lower than those of the control group 1,and the difference was statistically significant(P<0.05),but there was no significant difference in the VAS scores between the observation group and the control group 2 after the first and second weeks of treatment(P>0.05).(2)There was no significant difference in the scores of symptoms and signs among the three groups of patients before treatment(P>0.05).The scores of symptoms and signs in the first and second weeks after treatment were better than those before treatment(P<0.05).The scores of symptoms and signs of the observation group and the control group 2 in the first and second weeks after treatment were better than those of the control group 1,and the difference was statistically significant(P<0.05),but there was no significant difference in the scores of symptoms and signs between the observation group and the control group 2 after the first and second weeks of treatment(P>0.05).(3)There was no significant difference in the SF-36 scores among the three groups of patients before treatment(P>0.05).The SF-36 scores in the first and second weeks after treatment were higher than those before treatment(P<0.05).The SF-36 scores of the observation group and the control group 2 in the first and second weeks after treatment were better than those of the control group 1,and the difference was statistically significant(P<0.05),but there was no significant difference in the SF-36 scores between the observation group and the control group 2 after the first and second weeks of treatment(P>0.05).(4)The total effective rate in the observation group was 90.00%,and the control group 1 was 93.33%,which was significantly higher than 73.33%in the control group 1.(5)After treatment,the whole blood high shear viscosity,low shear viscosity and plasma viscosity of the three groups were lower than those before treatment(P<0.05);the related hemorheology indexes of the observation group and the control group were lower than those of the control group 1(P<0.05).There was no significant difference in the related hemorheology indexes between the observation group and the control group 2 after treatment(P>0.05).Conclusion:Compared with Jingtong granule group,Xiangbikang has a more significant effect in treating cervical spondylotic radiculopathy,which can significantly reduce the pain of patients,improve their accompanying symptoms,and improve the quality of life of patients.Xiangbikang can improve the hemorheology of patients with radicular cervical spondylosis,improve the blood microcirculation and blood viscosity,which is important for the relief of symptoms such as neck and shoulder pain of patients with radicular cervical spondylosis;compared with the group of Jingtong granule combined with celecoxib,the efficacy of Xiangbikang was comparable.In addition,the Xiangbikang group can avoid the incidence of gastrointestinal adverse reactions caused by Jingtong granule combined with celecoxib.