Clinical Observation Of The Treatment Of Spleen- Stomach Damp-heat Syndrome Irritable Bowel Syndrome With Predominant Diarrhea By Using Qushidaozhi Prescription

Objectives To observe the clinical efficacy of Qushidaozhi Prescription in the treatment of Spleen-stomach damp-heat syndrome irritable bowel syndrome with predominant diarrhea,and to provide new ideas and new methods for clinical treatment of irritable bowel syndrome with predominant diarrhea.Methods From October 2017 to October 2018,64 patients with spleen-stomach dampheat diarrhea-type irritable bowel syndrome who met the diagnostic criteria of Rome IV and the diagnostic criteria of TCM syndrome were screened in the spleen and stomach clinic of Shijiazhuang Traditional Chinese Medicine Hospital.Cases of subjects,Controlled research methods and stratified grouping methods were firstly divided into three levels according to the severity of the patient’s condition,and then divided into an odd array(treatment group)and an even array(control group)according to the order of visiting time;the treatment group was given Chinese medicine Qushidaozhi Prescription and the control group was given western medicine Trimetrine maleate tablets for 4weeks.Through questionnaires,the IBS-SSS individual scores and total scores,IBS-QOL total scores and TCM symptom individual scores and total scores of the two groups of patients before treatment,2 weeks of treatment and 4 weeks of treatment were recorded separately;Monitor patients for adverse reactions.Three months after the end of treatment,patients were followed up by telephone,WeChat,etc.,and the TCM symptom scores were recorded again to understand the patient’s recurrence.Finally,the statistical software SPSS20.0 was used to analyze the patient’s scores.The clinical effect and long-term recurrence of Spleen-stomach damp-heat syndrome irritable bowel syndrome with predominant diarrhea were compared between the treatment group and the control group.Results 1After treatment,the treatment group was cured in 3 cases,markedly effective in 16 cases,effective in 9 cases,and ineffective in 2 cases.In the control group,0 cases were cured,3 cases were markedly effective,19 cases were effective,and 8 cases were ineffective.The therapeutic effects of the two groups were statistically analyzed.Statistical significance(P<0.05),indicating that the clinical efficacy of the treatment group was significantly better than the control group.2In terms of improvement of the disease,the total score was compared.After 2 weeks of treatment,there was no statistically significant difference between the treatment group 183.43 ± 28.65 and the control group 194.97 ± 30.59(P>0.05),indicating that the treatment effect of the two groups was equivalent;After 4 weeks,the treatment group 146.03±22.04 compared with the control group 174.57±23.70,the difference was statistically significant(P<0.05),indicating that the treatment group was better than the control group.Compared with the control group,the difference of the frequency of abdominal pain and the impact on life was better than that of the control group after 2 weeks of treatment.The difference was statistically significant(P<0.05),and the other three dimensions were not statistically significant(P> 0.05);After 4 weeks of treatment,the effects of the five dimensions of the treatment group were better than the control group,the difference was statistically significant(P <0.05).3In terms of quality of life,after treatment for 2 weeks,the treatment group 44.10±16.09 compared with the control group 48.03±21.37,the statistical analysis showed no significant difference(P>0.05),indicating that the two groups were equally effective;treatment 4 The difference between the treatment group34.17±8.96 and the control group 40.23±11.72 was statistically significant(P<0.05),indicating that the treatment group was better than the control group.4The total scores ofTCM symptoms in the two groups were compared between the treatment group7.67±2.59,4.83±2.65 and the control group 11.00±3.66,8.57±2.94 after 2 weeks of treatment and 4 weeks of treatment.The difference between the two groups was statistically significant(P<0.05),indicating that the clinical efficacy of the treatment group was better than the control group.Compared with the control group,the difference between the two groups was better than that of the control group(P<0.05).There was no significant difference between the other aspects(P>0.05).0.05);After 4 weeks of treatment,the main treatment group was better than the control group in the four aspects of diarrhea,diarrhea and diarrhea,and emotional abnormalities.The difference was statistically significant(P<0.05).There were no statistics in other aspects.Academic significance(P>0.05).5At the follow-up 3 months after the end of the treatment,23 patients were followed up in the treatment group,3 patients had recurrence,and the recurrence rate was 13.04%.In the control group,20 patients were followed up and 8patients had recurrence.The recurrence rate was 40.00%.The significance of learning(P<0.05)indicates that the recurrence rate of the treatment group is lower than that of the control group.Conclusions Both the treatments for spleen-stomach damp-heat diarrhea-type irritable bowel syndrome have an effect;The comprehensive clinical effect of Qushidaozhi prescription is better than that of Trimebutine maleate,which can better improve the patient’s condition and improve the quality of life,and the long-term recurrence rate is low.Figure0;Table13;Reference100.