Treatment Of Ankylosing Spondylitis With Three-dimensional Balance Regulating Spinal Plot Combined With Du- Moxibustion Clinical Effect Study

Ankylosing spondylitis(AS)is a systemic disease of unknown cause,which is related to genetics,infection and autoimmune dysfunction.It mainly invades sacroiliac joints,hip joints and spinal column,and results in the pain of lumbar spine,limited movement of hip joint,and even spinal fusion and the stiffness and rigidity of joints in severe case,which causes patients unable to take care of themselves,thus bringing a heavy burden to family and society.Therefore,in this study,TCM external treatment-three-dimensional balanced correction of the spine combined with Du-moxibustion achieved good results in the treatment of AS.Objective: To explore the clinical effect of three-dimensional balanced correction of the spine combined with Du-moxibustion in the treatment of ankylosing spondylitis(AS),and to evaluate clinical effect scientifically and objectively for better clinical application.Methods: 176 patients with ankylosing spondylitis,according to the random number table method,were divided into two groups,i.e.,the control group and the experimental group.The control group was treated with western medicines: oral administration of sulfasalazine0.1g per day;and the experimental group was treated with three-dimensional balanced correction of the spine combined with Du-moxibustion: the cervical vertebra,thoracic vertebra and lumbar vertebra were treated with three-dimensional balanced correction;acupuncture was applied to the Jiaji acupoint,a pain point of the spine,and the Zusanliacupoints,the Taixi acupoints and the Fuliu acupoints at both sides;and Du moxibustion was applied to the Du Meridian on the back.The clinical effects were observed before the treatment,2 months and 6 months after the treatment,and the movement of the spine(anterior flexion,posterior flexion and lateral flexion),finger-to-ground distance,spine Kitel score,morning stiffness duration,morning stiffness degree VAS,nocturnal spinal pain VAS,spinal pain VAS,patient global assessment(PGA),whole body pain Liket score,Bath AS measurement index(BASMI),number of tendon tenderness points,TCM Syndrome score,BASDAI,Bath AS function index(BASFI),imaging mSASSS score,ESR and CRP were evaluated to judge if ASAS20,ASAS50 and ASAS70 were improved and met standards.Results: In the experimental group,the spinal Kitel score,morning stiffness duration,morning stiffness VAS,nocturnal spinal pain VAS,spinal pain VAS,patient global assessment(PGA),whole body pain Liket score,BASMI,finger-to-ground distance,number of tenderness points,TCM Syndrome score,BASDAI,BASFI and ESR decreased after treatment for 2 months,and the differences were statistically significant(P > 0.05).The movement of the spine was improved,the difference being statistically significant(P<0.05).mSASSS score and CRP did not change significantly(P>0.05).After 6 months of treatment,the spinal Kitel score,morning stiffness duration,morning stiffness VAS,nocturnal spinal pain VAS,spinal pain VAS,patient global assessment(PGA),whole body pain Liket score,BASMI,number of tenderness points,finger to ground distance,TCM syndrome score,BASDAI,BASFI,ESR and CRP decreased,the differences being statistically significant(P<0.05).The movement of the spine was improved,the difference being statistically significant(P < 0.05).mSASSS score did not change significantly(P > 0.05).After treatment for 2months and for 6 months,only morning stiffness duration,the movement of the spine and TCM syndrome scores decreased,the differences being statistically significant(P<0.05),and there were no significant changes in other parameters(P>0.05).In the control group,the spinal Kitel score,morning stiffness duration,morning stiffness VAS,nocturnal spinal pain VAS,spinal pain VAS,patient global assessment(PGA),whole body pain Liket score,BASMI,number of tendon tenderness points,BASDAI,BASFI,ESR /CRP all decreased after treatment for 2 months,and the differences were statistically significant(P < 0.05).There were no significant changes in finger-to-ground distance,the movement of the spine,TCM Syndrome and mSASSS score(P>0.05).After treatment for 6months,the spinal Kitel score,morning stiffness duration,morning stiffness VAS,nocturnal spinal pain VAS,spinal pain VAS,patient global assessment(PGA),whole body pain Liket score,BASMI,number of tendon tenderness points,BASDAI,BASFI,ESR/CRP all decreased after treatment for 2 months,the differences being statistically significant(P<0.05).There were no significant changes in finger-to-ground distance,the movement of the spine,TCM Syndrome and mSASSS score(P>0.05).There were no significant changes in all parameters after treatment for 2 months and for 6 months(P>0.05)Conclusion: oral administration of sulfasaldine and three-dimensional balanced correction of the spine combined with Du-moxibustion can alleviate the aseptic inflammatory reaction of AS and relieve clinical symptoms.Three-dimensional balanced correction of the spine combined with Du-moxibustion has better effect in alleviating aseptic inflammation,and effectively improves the motion of joints and restores the functions of joints,so as to effectively control the progress of active AS-induced bone destruction.