Correlation Between TCM Syndrome Types And MMP-9 And Carotid Atherosclerosis In Patients With Dyslipidemia

Objectivethrough the clinical observation of syndromes,patients with primary dyslipidemia found the TCM syndrome type distribution,and observe different syndromes and MMP-9,the correlation of carotid arteriosclerosis situation,thus to provide an indirect reference to the disease of TCM syndrome differentiation,and analyzes the relations between various blood fat index and the syndrome,try to provide the basis for microcosmic syndrome differentiation of traditional Chinese medicine.MethodsAccording to the corresponding into and exclusion criteria,collected in the Beijing university of Chinese medicine dongzhimen hospital and Beijing space flight center hospital in patients with primary dyslipidemia,signed the informed consent,gathering general information,fill in for syndrome questionnaire,collecting venous blood,patients with blood lipid and MMP-9 levels,the data were collected for statistical analysis,observing the index difference of dyslipidemia patients and healthy people;Observe the difference of indicators between different syndromes.Results1 The study found that 138 cases of patients with carotid artery atherosclerosis with dyslipidemia TCM syndrome type in frequency from high to low in turn is phlegm turbidity deter syndrome(24.6%)>and qi stagnation and blood stasis syndrome(23.9%)>spleen and kidney Yang deficiency syndrome(21%)>liver and kidney Yin deficiency syndrome(18.1%)>Yin hand syndrome(12.3%).Dyslipidemia in patients with type2 The serum TC level of the patients in each group was from high to low,which was in order of the phlegm turbidity.>spleen and kidney Yang deficiency syndrome,>qi stagnation and blood stasis syndrome,>the Yin deficiency syndrome of>,and no significant difference in TC distribution among the groups.The serum TG level of patients in each group was from high to low,which in order was the phlegm-turbidity suppressor syndrome>qi stagnation and blood stasis syndrome,>spleen and kidney Yang deficiency syndrome,>liver and kidney Yin deficiency syndrome,>Yin deficiency syndrome.The TG distribution was statistically significant in patients with qi stagnation and blood stasis,phlegm control group and Yin deficiency Yang group and liver and kidney Yin deficiency group.The serum hdl-c level of patients in each group was from high to low,which was in descending order of spleen and kidney Yang deficiency syndrome,>liver and kidney Yin deficiency syndrome,>qi stagnation blood stasis syndrome,BBB 3 sputum obstruction,and there was no significant difference among the groups.The serum ldl-c level of the patients in each group was from high to low in order of spleen and kidney Yang deficiency syndrome>phlegm.BBB 1 Yin deficiency Yang syndrome and>qi stagnation blood stasis syndrome,>liver and kidney Yin deficiency syndrome,there was no significant difference between the groups.3 Each group according to the size of MMP-9 followed by phlegm turbidity deter a certificate>deficiency of qi and blood stasis syndrome hand>spleen kidney Yang deficiency syndrome>liver-kidney Yin deficiency syndrome>health group.phlegm turbidity deter group and qi and blood stasis group was significantly higher than that of the spleen kidney Yang deficiency,liver and kidney Yin deficiency group and healthy group,the difference is statistically significant.4 The formation frequency of the plaques in each group was similar to that of the spleen and kidney Yang deficiency and the most,followed by qi stagnation and blood stasis,liver and kidney Yin deficiency and Yin deficiency Yang.Conclusion1 Phlegm blocking syndrome,qi stagnation blood stasis syndrome,spleen and kidney Yang deficiency syndrome are the main syndromes of dyslipidemia,and the frequency of liver and kidney Yin deficiency syndrome and Yin deficiency syndrome is less frequent.2 Phlegm turbidity deter a card and TG qi and blood stasis patients were significantly higher than that of other groups,and phlegm turbidity repression and spleen kidney Yang deficiency group TC,LDH-C higher than that of other groups,also can be the TC and TG levels as corresponding syndrome dialectical indirect reference.3 The mmp-9 distribution was also significantly correlated with phlegm blocking and qi stagnation blood stasis,and the mmp-9 water in the case group was higher than that of the healthy people.4 The formation and stenosis of.carotid plaques are seen in the pathogenesis of phlegm,kidney Yang deficiency,qi stagnation and blood stasis,etc.,which are in line with the pathogenesis of TCM phlegm stasis,and the carotid artery unstable plaques are also more widely distributed in the above syndromes.